APC/Cyanine7 anti-human CD3 Antibody
- 产品名称：
- APC/Cyanine7 anti-human CD3 Antibody
- 产品类别：
- 抗体
- 产品编号：
- 344817
- 产品应用：
- 344817
[价格]
| 规格 |
价格 |
库存 |
| 25tests |
￥ 1806 |
1 |
- Verified Reactivity
- Human
- Reported Reactivity
- Chimpanzee
- Antibody Type
- Monoclonal
- Host Species
- Mouse
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
- Preparation
- The antibody was purified by affinity chromatography, and conjugated with APC/Cyanine7 under optimal conditions.
- Concentration
- Lot-specific (to obtain lot-specific concentration, please enter the lot number in our Concentration and Expiration Lookup or Certificate of Analysis online tools.)
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
- Application
-
FC - Quality tested
- Recommended Usage
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 ?l per million cells in 100 ?l staining volume or 5 ?l per 100 ?l of whole blood.
- Excitation Laser
- Red Laser (633 nm)
- Application Notes
Additional reported application (for the relevant formats) include: immunohistochemical staining of frozen tissue sections4,5,8, immunofluorescent staining6, and Western blotting3.
- Additional Product Notes
- BioLegend is in the process of converting the name APC/Cy7 to APC/Cyanine7. The dye molecule remains the same, so you should expect the same quality and performance from our APC/Cyanine7 products. Please contact Technical Service if you have any questions.
- Application References
(PubMed link indicates BioLegend citation) -
- Kan EA, et al. 1983. J. Immunol. 131:536.
- Wood GS, et al. 1985. Am. J. Pathol. 120:371.
- Van Dongen JJM, et al. 1988. Blood 71:603. (WB)
- Haringman JJ, et al. 2005. Arthritis Res. Ther. 7:R862. (IHC)
- Carbone A, et al. 1999. Blood 93:2319. (IHC)
- Goval JJ, et al. 2006. J. Histochem. Cytochem. 54:75. (IF)
- Rutjens E, et al. 2007. J. Immunol. 178:1702.
- Kap Y, et al. 2009. J. Histochem. Cytochem. 57:1159. (IHC)
- Yoshino N, et al. 2000. Exp. Anim. (Tokyo) 49:97. (FC)
- Product Citations
-
- Calabrese DR, et al. 2020. J Clin Invest. . PubMed
- Muliaditan T, et al. 2021. Cell Rep Med. 2:100457. PubMed
- Kagoya Y, et al. 2018. Nat Commun. 9:1915. PubMed
- Marques RM, et al. 2021. Cell Death Differ. 28:3140. PubMed
- Turner JA, et al. 2020. Immunity. 53:1202. PubMed
- Neidleman J, et al. 2020. Cell Rep Med. 100081:1. PubMed
- Beatson RE, et al. 2021. Cell Rep Med. 2:100473. PubMed
- Guerrero A, et al. 2022. Nat Aging. 2:851. PubMed
- Zhang B, et al. 2021. Nat Biomed Eng. 5:1288. PubMed
- Thompson EA, et al. 2021. Cell Rep. 108863:34. PubMed
- Batikan O, et al. 2022. J Coll Physicians Surg Pak. 32:1004. PubMed
- Chao Y, et al. 2014. J Leukoc Biol. 96:1037. PubMed
- Graham C, et al. 2021. Immunity. 54(6):1276-1289.e6. PubMed
- Christiansen M, et al. 2020. Front Immunol. 10:3022. PubMed
- Egedal JH, et al. 2021. Mucosal Immunol. 14:1203. PubMed
- Xie G, et al. 2021. Cell Reports. 35(4):109038. PubMed
- Salazar-Camarena DC, et al. 2020. Sci Rep. 10:6236. PubMed
- Mackroth M, et al. 2016. PLoS Pathog. 12:e1005909. PubMed
- Mothe B, et al. 2020. Front Immunol. 1.029861111. PubMed
- Tang X, et al. 2020. Sci Adv. 6:eaaz0374. PubMed
- Yamaguchi K, et al. 2018. Cancer Sci. 109:3032. PubMed
- RRID
- AB_10644011 (BioLegend Cat. No. 344817) AB_10645474 (BioLegend Cat. No. 344818)
- Structure
- Ig superfamily, with the subunits of CD3γ, CD3δ, CD3ζ, (CD247) and TCR (α/β or γ/δ) forms CD3/TCR complex, 20 kD
- Distribution
-
Mature T and NK T cells, during thymocyte differentiation
- Function
- Antigen recognition, signal transduction, T cell activation
- Ligand/Receptor
- Peptide antigen bound to MHC
- Cell Type
- NKT cells, T cells, Tregs
- Biology Area
- Immunology, Innate Immunity
- Molecular Family
- CD Molecules, TCRs
- Antigen References
-
1. Barclay N, et al. 1993. The Leucocyte FactsBook. Academic Press. San Diego.
2. Beverly P, et al. 1981. Eur. J. Immunol. 11:329.
3. Lanier L, et al. 1986. J. Immunol. 137:2501.
- Gene ID
- 916 View all products for this Gene ID
- UniProt
- View information about CD3 on UniProt.org
