PerCP/Cyanine5.5 anti-human CD19 Antibody
- 产品名称：
- PerCP/Cyanine5.5 anti-human CD19 Antibody
- 产品类别：
- 抗体
- 产品编号：
- 363015
- 产品应用：
- 363015
[价格]
| 规格 |
价格 |
库存 |
| 25tests |
￥ 2464 |
1 |
- Verified Reactivity
- Human
- Antibody Type
- Monoclonal
- Host Species
- Mouse
- Immunogen
- NALM1 + NALM16 cells
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
- Preparation
- The antibody was purified by affinity chromatography and conjugated with PerCP/Cyanine5.5 under optimal conditions.
- Concentration
- Lot-specific (to obtain lot-specific concentration, please enter the lot number in our Concentration and Expiration Lookup or Certificate of Analysis online tools.)
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
- Application
-
FC - Quality tested
- Recommended Usage
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 ?l per million cells in 100 ?l staining volume or 5 ?l per 100 ?l of whole blood.
* PerCP/Cyanine5.5 has a maximum absorption of 482 nm and a maximum emission of 690 nm.
- Application Notes
Clone SJ25C1 partially blocks anti-human CD19 clones HIB19 and 4G7 staining based on in-house testing
- Additional Product Notes
- BioLegend is in the process of converting the name PerCP/Cy5.5 to PerCP/Cyanine5.5. The dye molecule remains the same, so you should expect the same quality and performance from our PerCP/Cyanine5.5 products. Contact Technical Service if you have any questions.
- Product Citations
-
- Imbrechts M, et al. 2022. iScience. 25:104705. PubMed
- Christopher S Garris et al. 2018. Immunity. 49(6):1148-1161 . PubMed
- Yang L, et al. 2020. Genes Dis. 7:128. PubMed
- Hakki S, et al. 2022. Sci Rep. 12:1427. PubMed
- Zhu YP et al. 2018. Cell reports. 24(9):2329-2341 . PubMed
- RRID
- AB_2564206 (BioLegend Cat. No. 363015) AB_2564207 (BioLegend Cat. No. 363016)
- Structure
- Ig superfamily, type I transmembrane glycoprotein, 95 kD.
- Distribution
-
B lineage (except plasma cells), follicular dendritic cells.
- Function
- B cell activation and differentiation.
- Interaction
- Forms a complex with CD21, CD81 and CD225 in the membrane of mature B cells and interacts with VAV and LYN. It also interacts with GRAB2 and SOS when phosphorylated on Tyr-348 and/or Tyr-378 and with PLCG2 when phosphorylated on Tyr-409.
- Ligand/Receptor
- Forms complex with CD21 (CR2) and CD81 (TAPA-1), BCR co-receptor.
- Cell Type
- B cells, Dendritic cells
- Biology Area
- Costimulatory Molecules, Immunology
- Molecular Family
- CD Molecules
- Antigen References
-
1. Tedder T, et al. 1994. Immunol. Today 15:437.
2. Bradbury L, et al. 1993. J. Immunol. 151:2915.
- Gene ID
- 930 View all products for this Gene ID
- UniProt
- View information about CD19 on UniProt.org
