APC/Cyanine7 anti-human CD19 Antibody
- 产品名称：
- APC/Cyanine7 anti-human CD19 Antibody
- 产品类别：
- 抗体
- 产品编号：
- 363009
- 产品应用：
- 363009
[价格]
| 规格 |
价格 |
库存 |
| 25tests |
￥ 1582 |
1 |
- Verified Reactivity
- Human
- Antibody Type
- Monoclonal
- Host Species
- Mouse
- Immunogen
- NALM1 + NALM16 cells
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
- Preparation
- The antibody was purified by affinity chromatography and conjugated with APC/Cyanine7 under optimal conditions.
- Concentration
- Lot-specific (to obtain lot-specific concentration, please enter the lot number in our Concentration and Expiration Lookup or Certificate of Analysis online tools.)
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
- Application
-
FC - Quality tested
- Recommended Usage
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 ?l per million cells in 100 ?l staining volume or 5 ?l per 100 ?l of whole blood.
- Excitation Laser
- Red Laser (633 nm)
- Application Notes
Clone SJ25C1 partially blocks anti-human CD19 clones HIB19 and 4G7 staining based on in-house testing
- Additional Product Notes
- BioLegend is in the process of converting the name APC/Cy7 to APC/Cyanine7. The dye molecule remains the same, so you should expect the same quality and performance from our APC/Cyanine7 products. Please contact Technical Service if you have any questions.
- Product Citations
-
- Cirovic B, et al. 2020. Cell Host & Microbe. 28(2):322-334. PubMed
- van der Heiden M, et al. 2020. Scand J Immunol. e13005:. PubMed
- Manukyan G, et al. 2020. Auto Immun Highlights. 11:5. PubMed
- Thaker YR, et al. 2022. Front Oncol. 12:884196. PubMed
- Kaneko N, et al. 2020. Cell. 183(1):143-157.e13. PubMed
- Kerkman PF, Kempers AC 2016. Ann Rheum Dis. 75(12):2201-2207. PubMed
- Thompson EA, et al. 2021. Cell Rep. 108863:34. PubMed
- Dos Santos JC, et al. 2019. Cell Rep. 28:2659. PubMed
- Rabold K, et al. 2022. Nat Commun. 13:6149. PubMed
- Pekayvaz K, et al. 2022. Nat Commun. 13:1018. PubMed
- RRID
- AB_2564192 (BioLegend Cat. No. 363009) AB_2564193 (BioLegend Cat. No. 363010)
- Structure
- Ig superfamily, type I transmembrane glycoprotein, 95 kD.
- Distribution
-
B lineage (except plasma cells), follicular dendritic cells.
- Function
- B cell activation and differentiation.
- Interaction
- Forms a complex with CD21, CD81 and CD225 in the membrane of mature B cells and interacts with VAV and LYN. It also interacts with GRAB2 and SOS when phosphorylated on Tyr-348 and/or Tyr-378 and with PLCG2 when phosphorylated on Tyr-409.
- Ligand/Receptor
- Forms complex with CD21 (CR2) and CD81 (TAPA-1), BCR co-receptor.
- Cell Type
- B cells, Dendritic cells
- Biology Area
- Costimulatory Molecules, Immunology
- Molecular Family
- CD Molecules
- Antigen References
-
1. Tedder T, et al. 1994. Immunol. Today 15:437.
2. Bradbury L, et al. 1993. J. Immunol. 151:2915.
- Gene ID
- 930 View all products for this Gene ID
- UniProt
- View information about CD19 on UniProt.org
