Purified anti-human CD156c (ADAM10) Antibody
- 产品名称：
- Purified anti-human CD156c (ADAM10) Antibody
- 产品类别：
- 抗体
- 产品编号：
- 352702
- 产品应用：
- 352702
- Verified Reactivity
- Human
- Reported Reactivity
- African Green, Baboon, Cynomolgus, Rhesus
- Antibody Type
- Monoclonal
- Host Species
- Mouse
- Immunogen
- Human A375 cell lines
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
- Preparation
- The antibody was purified by affinity chromatography.
- Concentration
- 0.5 mg/ml
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C.
- Application
-
FC - Quality tested
- Recommended Usage
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤1.0 ?g per million cells in 100 ?l volume. It is recommended that the reagent be titrated for optimal performance for each application.
- Product Citations
-
- Lorenzen I, et al. 2016. Sci Rep. 6:35067. PubMed
- Vanderboom PM, et al. 2021. Cell Reports Methods. 1(3):. PubMed
- Künzel U et al. 2018. eLife. 7 pii: e35012. PubMed
- RRID
- AB_10897813 (BioLegend Cat. No. 352702)
- Structure
- Consist of signal sequence, a N-terminal prodomain followed by a catalytic proteinase domain containing a zinc-binding motif, a disintegrin, cysteine-rich transmembrane, and a cytoplasmatic domain
- Distribution
-
Ubiquitously expressed on most of the cell types
- Function
- Acts as an efficient α-secretase
- Interaction
- Proteolysis the amyloid precursor protein (APP)
- Cell Type
- B cells, Dendritic cells, Tregs
- Biology Area
- Cell Adhesion, Cell Biology, Immunology, Innate Immunity, Neurodegeneration, Neuroscience, Protein Misfolding and Aggregation, Signal Transduction
- Molecular Family
- Adhesion Molecules, CD Molecules
- Antigen References
-
1. Edwards DR, et al. 2008. Mol. Aspects Med. 29:258.
2. Anders A, et al. 2001. FASEB J. 15:1837.
3. Endres K, et al. 2010. FEBS J. 277:1585.
4. Mochizuki S, et al. 2007. Cancer Sci. 98:621.
- Gene ID
- 4684 View all products for this Gene ID
- UniProt
- View information about CD156c on UniProt.org
