首页 > 抗体蛋白 > 抗体
PE anti-human CD156c (ADAM10) Antibody
产品名称:
PE anti-human CD156c (ADAM10) Antibody
产品类别:
抗体
产品编号:
352703
产品应用:
352703
[价格]
规格 价格 库存
25tests ¥ 2142 1

产品详情

Product Details

Verified Reactivity
Human
Reported Reactivity
African Green, Baboon, Cynomolgus, Rhesus
Antibody Type
Monoclonal
Host Species
Mouse
Immunogen
Human A375 cell lines
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
Preparation
The antibody was purified by affinity chromatography and conjugated with PE under optimal conditions.
Concentration
Lot-specific (to obtain lot-specific concentration, please enter the lot number in our Concentration and Expiration Lookup or Certificate of Analysis online tools.)
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
Application

FC - Quality tested

Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 ?l per million cells in 100 ?l staining volume or 5 ?l per 100 ?l of whole blood.

Excitation Laser
Blue Laser (488 nm)
Green Laser (532 nm)/Yellow-Green Laser (561 nm)
Product Citations
  1. Lee JH, et al. 2022. EBioMedicine. 77:103903. PubMed
  2. Shambat S, et al. 2015. Dis Model Mech. 8: 1413 - 1425. PubMed
  3. Popov L, et al. 2015. Proc Natl Acad Sci U S A. 10.1073/pnas.1510265112. PubMed
  4. Franke M, et al. 2016. J Biol Chem. 291: 10551 - 10561. PubMed
  5. Riethmueller S, et al. 2016. Sci Rep. 6: 25550. PubMed
  6. Popov L, et al. 2015. Proc Natl Acad Sci U S A. 112: 14337 - 14342. PubMed
  7. Triplett KD, et al. 2019. Sci Rep. 9:1343. PubMed
  8. Ostalecki C, et al. 2016. EBioMedicine. 13:294-304. PubMed
RRID
AB_10900811 (BioLegend Cat. No. 352703) AB_10896790 (BioLegend Cat. No. 352704)

Antigen Details

Structure
Consist of signal sequence, a N-terminal prodomain followed by a catalytic proteinase domain containing a zinc-binding motif, a disintegrin, cysteine-rich transmembrane, and a cytoplasmatic domain
Distribution

Ubiquitously expressed on most of the cell types

Function
Acts as an efficient α-secretase
Interaction
Proteolysis the amyloid precursor protein (APP)
Cell Type
B cells, Dendritic cells, Tregs
Biology Area
Cell Adhesion, Cell Biology, Immunology, Innate Immunity, Neurodegeneration, Neuroscience, Protein Misfolding and Aggregation, Signal Transduction
Molecular Family
Adhesion Molecules, CD Molecules
Antigen References

1. Edwards DR, et al. 2008. Mol. Aspects Med. 29:258.
2. Anders A, et al. 2001. FASEB J. 15:1837.
3. Endres K, et al. 2010. FEBS J. 277:1585.
4. Mochizuki S, et al. 2007. Cancer Sci. 98:621.

Gene ID
4684 View all products for this Gene ID
UniProt
View information about CD156c on UniProt.org

联系我们

TEL:021-34661275  点击拨打热线