PE anti-human CD156c (ADAM10) Antibody
- 产品名称：
- PE anti-human CD156c (ADAM10) Antibody
- 产品类别：
- 抗体
- 产品编号：
- 352703
- 产品应用：
- 352703
[价格]
| 规格 |
价格 |
库存 |
| 25tests |
￥ 2142 |
1 |
- Verified Reactivity
- Human
- Reported Reactivity
- African Green, Baboon, Cynomolgus, Rhesus
- Antibody Type
- Monoclonal
- Host Species
- Mouse
- Immunogen
- Human A375 cell lines
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
- Preparation
- The antibody was purified by affinity chromatography and conjugated with PE under optimal conditions.
- Concentration
- Lot-specific (to obtain lot-specific concentration, please enter the lot number in our Concentration and Expiration Lookup or Certificate of Analysis online tools.)
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
- Application
-
FC - Quality tested
- Recommended Usage
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 ?l per million cells in 100 ?l staining volume or 5 ?l per 100 ?l of whole blood.
- Excitation Laser
- Blue Laser (488 nm)
Green Laser (532 nm)/Yellow-Green Laser (561 nm)
- Product Citations
-
- Lee JH, et al. 2022. EBioMedicine. 77:103903. PubMed
- Shambat S, et al. 2015. Dis Model Mech. 8: 1413 - 1425. PubMed
- Popov L, et al. 2015. Proc Natl Acad Sci U S A. 10.1073/pnas.1510265112. PubMed
- Franke M, et al. 2016. J Biol Chem. 291: 10551 - 10561. PubMed
- Riethmueller S, et al. 2016. Sci Rep. 6: 25550. PubMed
- Popov L, et al. 2015. Proc Natl Acad Sci U S A. 112: 14337 - 14342. PubMed
- Triplett KD, et al. 2019. Sci Rep. 9:1343. PubMed
- Ostalecki C, et al. 2016. EBioMedicine. 13:294-304. PubMed
- RRID
- AB_10900811 (BioLegend Cat. No. 352703) AB_10896790 (BioLegend Cat. No. 352704)
- Structure
- Consist of signal sequence, a N-terminal prodomain followed by a catalytic proteinase domain containing a zinc-binding motif, a disintegrin, cysteine-rich transmembrane, and a cytoplasmatic domain
- Distribution
-
Ubiquitously expressed on most of the cell types
- Function
- Acts as an efficient α-secretase
- Interaction
- Proteolysis the amyloid precursor protein (APP)
- Cell Type
- B cells, Dendritic cells, Tregs
- Biology Area
- Cell Adhesion, Cell Biology, Immunology, Innate Immunity, Neurodegeneration, Neuroscience, Protein Misfolding and Aggregation, Signal Transduction
- Molecular Family
- Adhesion Molecules, CD Molecules
- Antigen References
-
1. Edwards DR, et al. 2008. Mol. Aspects Med. 29:258.
2. Anders A, et al. 2001. FASEB J. 15:1837.
3. Endres K, et al. 2010. FEBS J. 277:1585.
4. Mochizuki S, et al. 2007. Cancer Sci. 98:621.
- Gene ID
- 4684 View all products for this Gene ID
- UniProt
- View information about CD156c on UniProt.org
