APC anti-human CD156c (ADAM10) Antibody
- 产品名称：
- APC anti-human CD156c (ADAM10) Antibody
- 产品类别：
- 抗体
- 产品编号：
- 352705
- 产品应用：
- 352705
[价格]
| 规格 |
价格 |
库存 |
| 25tests |
￥ 2156 |
1 |
- Verified Reactivity
- Human
- Reported Reactivity
- African Green, Baboon, Cynomolgus, Rhesus
- Antibody Type
- Monoclonal
- Host Species
- Mouse
- Immunogen
- Human A375 cell lines
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
- Preparation
- The antibody was purified by affinity chromatography and conjugated with APC under optimal conditions.
- Concentration
- Lot-specific (to obtain lot-specific concentration, please enter the lot number in our Concentration and Expiration Lookup or Certificate of Analysis online tools.)
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
- Application
-
FC - Quality tested
- Recommended Usage
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 ?l per million cells in 100 ?l staining volume or 5 ?l per 100 ?l of whole blood.
- Excitation Laser
- Red Laser (633 nm)
- Product Citations
-
- Shemesh A, et al. 2022. J Exp Med. 219:. PubMed
- RRID
- AB_2563172 (BioLegend Cat. No. 352705) AB_2563173 (BioLegend Cat. No. 352706)
- Structure
- Consist of signal sequence, a N-terminal prodomain followed by a catalytic proteinase domain containing a zinc-binding motif, a disintegrin, cysteine-rich transmembrane, and a cytoplasmatic domain
- Distribution
-
Ubiquitously expressed on most of the cell types
- Function
- Acts as an efficient α-secretase
- Interaction
- Proteolysis the amyloid precursor protein (APP)
- Cell Type
- B cells, Dendritic cells, Tregs
- Biology Area
- Cell Adhesion, Cell Biology, Immunology, Innate Immunity, Neurodegeneration, Neuroscience, Protein Misfolding and Aggregation, Signal Transduction
- Molecular Family
- Adhesion Molecules, CD Molecules
- Antigen References
-
1. Edwards DR, et al. 2008. Mol. Aspects Med. 29:258.
2. Anders A, et al. 2001. FASEB J. 15:1837.
3. Endres K, et al. 2010. FEBS J. 277:1585.
4. Mochizuki S, et al. 2007. Cancer Sci. 98:621.
- Gene ID
- 4684 View all products for this Gene ID
- UniProt
- View information about CD156c on UniProt.org
