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Purified anti-mouse CX3CR1 Antibody
产品名称:
Purified anti-mouse CX3CR1 Antibody
产品类别:
抗体
产品编号:
149002
产品应用:
149002
[价格]
规格 价格 库存
100µg ¥ 3710 1

产品详情

Product Details

Verified Reactivity
Mouse
Antibody Type
Monoclonal
Host Species
Mouse
Immunogen
Mouse CX3CR1-transfected cells
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide with stabilizer.
Preparation
The antibody was purified by affinity chromatography.
Concentration
0.5 mg/ml
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C.
Application

FC - Quality tested

Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤0.5 ?g per million cells in 100 ?l volume. It is recommended that the reagent be titrated for optimal performance for each application.

Application Notes

View more applications data for a different format of this clone in our Scientific Poster Library.

Product Citations
  1. Hutton C, et al. 2021. Cancer Cell. 39:1227. PubMed
  2. Khan KA, et al. 2020. NPJ Breast Cancer. 6:29. PubMed
  3. Chen L, et al. 2019. Nat Commun. 3.553472222. PubMed
  4. Carpenter SM, et al. 2017. PLoS Pathog. 13:e1006704. PubMed
  5. Khan KA, et al. 2020. NPJ Breast Cancer. 6:29. PubMed
  6. Mrdjen D et al. 2018. Immunity. 48(2):380-395 . PubMed
  7. McDonald B, et al. 2020. Cell Host Microbe. 28(5):660-668.e4. PubMed
  8. Ejima R, et al. 2021. Nutrients. 13:. PubMed
  9. Gubin MM, et al. 2018. Cell. 175:1014. PubMed
  10. Yang W, et al. 2019. Nat Commun. 1.163888889. PubMed
  11. Jordan S, et al. 2020. Cell. 178(5):1102-1114.e17.. PubMed
  12. Nakayama H, et al. 2018. Nat Commun. 9:20222. PubMed
RRID
AB_2564313 (BioLegend Cat. No. 149002)

Antigen Details

Structure
G-protein coupled receptor, 7 transmembrane regions, 40 kD.
Distribution

Resident and alternatively activated macrophages (M2), subset of monocytes, dendritic cells (DCs), natural killer cells (NK), subset of memory T cells, mast cells, glial cells, and astrocytes.

Function
Involved in cell recruitment during inflammation, participates in cell adhesion and extravasation from blood vessels, coreceptor for HIV1.
Ligand/Receptor
CX3CL1 (fractalkine, neurotactin).
Cell Type
Astrocytes, Dendritic cells, Macrophages, Mast cells, Microglia, Monocytes, NK cells, T cells
Biology Area
Cell Adhesion, Cell Biology, Immunology, Innate Immunity, Neuroscience, Neuroscience Cell Markers
Molecular Family
Cytokine/Chemokine Receptors, GPCR
Antigen References

1. Ponzetta A, et al. 2013. J. Immunol. 191:5684.
2. Jacquelin S, et al. 2013. Blood. 122:674.
3. Garcia JA, et al. 2013. J. Immunol. 191:1063.
4. Lee YS, et al. 2013. Cell. 153:413.
5. Shechter R, et al. 2013. Immunity. 38:555.

Gene ID
13051 View all products for this Gene ID
UniProt
View information about CX3CR1 on UniProt.org

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