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PE/Cyanine7 anti-mouse CX3CR1 Antibody
产品名称：
PE/Cyanine7 anti-mouse CX3CR1 Antibody
产品类别：
抗体
产品编号：
149015
产品应用：
149015
[价格]
规格 价格 库存
25µg ￥ 2464 1

产品详情

Product Details

Verified Reactivity
Mouse
Antibody Type
Monoclonal
Host Species
Mouse
Immunogen
Mouse CX3CR1-transfected cells
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide; may contain stabilizer.
Preparation
The antibody was purified by affinity chromatography and conjugated with PE/Cyanine7 under optimal conditions.
Concentration
0.2 mg/ml
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
Application

FC - Quality tested
Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤0.015 ?g per million cells in 100 ?l volume. It is recommended that the reagent be titrated for optimal performance for each application.

Excitation Laser
Blue Laser (488 nm)
Green Laser (532 nm)/Yellow-Green Laser (561 nm)
Application Notes

View more applications data for a different format of this clone in our Scientific Poster Library.

Additional Product Notes

BioLegend is in the process of converting the name PE/Cy7 to PE/Cyanine7. The dye molecule remains the same, so you should expect the same quality and performance from our PE/Cyanine7 products. Please contact Technical Service if you have any questions.

Product Citations
  1. Kim JS, et al. 2020. Immunity. 54(1):176-190.e7. PubMed
  2. Lefebvre MN, et al. 2021. Cell Rep. 37:109956. PubMed
  3. Moudra A, et al. 2021. J Immunol. 206:2109. PubMed
  4. Myers LM, et al. 2019. Nat Commun. 10:794. PubMed
  5. Chattopadhyay A, et al. 2018. Sci Rep. 8:9032. PubMed
  6. Donley DW, et al. 2021. PLOS ONE. 16(5):e0250606. PubMed
  7. Samarchith P Kurup et al. 2019. Cell host & microbe. 25(4):565-577 . PubMed
  8. Zhang X, et al. 2020. Elife. 9:00. PubMed
  9. Chen X et al. 2017. Cell stem cell. 21(6):747-760 . PubMed
  10. Dietmar Herndler‐Brandstetter et al. 2018. Immunity. 48(4):716-729 . PubMed
  11. Fan KQ, et al. 2020. Cell. 179(4):864-879.e19.. PubMed
  12. Witkowski MT, et al. 2020. Cancer Cell. 37:867. PubMed
  13. Van Braeckel-Budimir N, et al. 2018. Cell Rep. 24:3374. PubMed
  14. Dobson HE, et al. 2020. Mucosal Immunol. 0.901388889. PubMed
  15. Ledo JH, et al. 2020. PLoS One. e0237773:15. PubMed
  16. Di Campli MP, et al. 2020. Eur Respir J. . PubMed
  17. Di Pilato M, et al. 2021. Cell. 184(17):4512-4530.e22. PubMed
  18. Schnoegl D, et al. 2022. Front Immunol. 13:909270. PubMed
  19. Rochford I, et al. 2021. Am J Physiol Lung Cell Mol Physiol. 321:L686. PubMed
  20. Wang J, et al. 2020. Cell. 183(7):1867-1883.e26. PubMed
  21. Lai NY, et al. 2020. Cell. 180:33:00. PubMed
  22. Ledo JH, et al. 2020. Mol Psychiatry. . PubMed
RRID
AB_2565699 (BioLegend Cat. No. 149015) AB_2565700 (BioLegend Cat. No. 149016)

Antigen Details

Structure
G-protein coupled receptor, 7 transmembrane regions, 40 kD.
Distribution

Resident and alternatively activated macrophages (M2), subset of monocytes, dendritic cells (DCs), natural killer cells (NK), subset of memory T cells, mast cells, glial cells, and astrocytes.

Function
Involved in cell recruitment during inflammation, participates in cell adhesion and extravasation from blood vessels, coreceptor for HIV1.
Ligand/Receptor
CX3CL1 (fractalkine, neurotactin).
Cell Type
Astrocytes, Dendritic cells, Macrophages, Mast cells, Microglia, Monocytes, NK cells, T cells
Biology Area
Cell Adhesion, Cell Biology, Immunology, Innate Immunity, Neuroscience, Neuroscience Cell Markers
Molecular Family
Cytokine/Chemokine Receptors, GPCR
Antigen References

1. Ponzetta A, et al. 2013. J. Immunol. 191:5684.
2. Jacquelin S, et al. 2013. Blood. 122:674.
3. Garcia JA, et al. 2013. J. Immunol. 191:1063.
4. Lee YS, et al. 2013. Cell. 153:413.
5. Shechter R, et al. 2013. Immunity. 38:555.

Gene ID
13051 View all products for this Gene ID
UniProt
View information about CX3CR1 on UniProt.org

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