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PE anti-mouse CX3CR1 Antibody
产品名称:
PE anti-mouse CX3CR1 Antibody
产品类别:
抗体
产品编号:
149005
产品应用:
149005
[价格]
规格 价格 库存
25µg ¥ 1806 1

产品详情

Product Details

Verified Reactivity
Mouse
Antibody Type
Monoclonal
Host Species
Mouse
Immunogen
Mouse CX3CR1-transfected cells
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide; may contain stabilizer.
Preparation
The antibody was purified by affinity chromatography and conjugated with PE under optimal conditions.
Concentration
0.2 mg/ml
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
Application

FC - Quality tested

Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤0.03 ?g per million cells in 100 ?l volume. It is recommended that the reagent be titrated for optimal performance for each application.

Excitation Laser
Blue Laser (488 nm)
Green Laser (532 nm)/Yellow-Green Laser (561 nm)
Application Notes

View more applications data for a different format of this clone in our Scientific Poster Library.

Product Citations
  1. Zhao XF, et al. 2020. The Journal of Neuroscience. 40(40):7593-7608. PubMed
  2. Mathur R, et al. 2019. Mucosal Immunol. 12:612. PubMed
  3. Dong L, et al. 2021. Cancer Cell. . PubMed
  4. Kaur K, et al. 2021. Cell Rep. 37:110178. PubMed
  5. Vicario N, et al. 2021. Cell Death Disease. 12(7):625. PubMed
  6. Bauché D et al. 2018. Immunity. 49(2):342-352 . PubMed
  7. Maisonneuve C, et al. 2021. Cell Reports. 34(4):108677. PubMed
  8. Misumi I et al. 2019. Cell Rep. 27(2):514-524 . PubMed
  9. Anderson CK et al. 2019. Cell Rep. 27(2):537-548 . PubMed
  10. Cao W, et al. 2017. Immunity. 47:1182. PubMed
  11. Xiao P, et al. 2019. J Exp Med. 216:337. PubMed
  12. Trompette A, et al. 2022. Mucosal Immunol. :. PubMed
  13. Stump CT, et al. 2021. Open Biol. 11:210245. PubMed
  14. Oladiran O, et al. 2021. J Neuroinflammation. 77:18. PubMed
  15. Hulsmans M et al. 2017. Cell. 169(3):510-522 . PubMed
  16. Leylek R, et al. 2019. Cell Rep. 29:3736. PubMed
  17. Sanchis P, et al. 2020. Glia. 68:999. PubMed
  18. He J, et al. 2019. J Clin Invest. 130. PubMed
  19. Deczkowska A, et al. 2017. Nat Commun. 8:717. PubMed
  20. Liu S, et al. 2020. Cell Host & Microbe. 26(6):779-794.e8.. PubMed
  21. Luo J et al. 2018. Immunity. 49(1):107-119 . PubMed
  22. Frost JN, et al. 2021. Med (N Y). 2:164. PubMed
  23. Maulloo CD, et al. 2021. Front Immunol. 12:714842. PubMed
  24. Baxter PS, et al. 2021. Cell Rep. 34:108882. PubMed
  25. Fan A, et al. 2020. J Neuroinflammation. 17:179. PubMed
  26. Morikawa M, et al. 2016. PLoS One. 11:e0163607. PubMed
  27. Guendel F, et al. 2020. Immunity. 53(5):1015-1032.e8. PubMed
  28. Bordt EA, et al. 2020. STAR Protoc. :1. PubMed
  29. Ko HJ, et al. 2020. Front Immunol. 1897:11. PubMed
  30. Dal-Secco D, et al. 2015. J Exp Med. 212:447. PubMed
  31. Collins N, et al. 2020. Cell. 178(5):1088-1101.e15.. PubMed
  32. Stefan KL, et al. 2020. Cell. 1312:183. PubMed
  33. Peruzzotti-Jametti L, et al. 2018. Cell Stem Cell. 22:355. PubMed
  34. Castro‐Dopico T et al. 2019. Immunity. 50(4):1099-1114 . PubMed
  35. Zhu G, et al. 2022. Front Microbiol. 12:806902. PubMed
  36. Sharma R, et al. 2021. J Neuroinflammation. 72:18. PubMed
  37. Alam MM, et al. 2021. eneuro. 8(1):. PubMed
  38. Heckler M, et al. 2021. Cancer Discov. Online ahead of prin. PubMed
  39. Oladiran O, et al. 2021. Front Immunol. 12:720733. PubMed
  40. Kubli SP, et al. 2019. Nat Commun. 10:2678. PubMed
  41. Aurélien Trompette et al. 2018. Immunity. 48(5):992-1005 . PubMed
RRID
AB_2564314 (BioLegend Cat. No. 149005) AB_2564315 (BioLegend Cat. No. 149006)

Antigen Details

Structure
G-protein coupled receptor, 7 transmembrane regions, 40 kD.
Distribution

Resident and alternatively activated macrophages (M2), subset of monocytes, dendritic cells (DCs), natural killer cells (NK), subset of memory T cells, mast cells, glial cells, and astrocytes.

Function
Involved in cell recruitment during inflammation, participates in cell adhesion and extravasation from blood vessels, coreceptor for HIV1.
Ligand/Receptor
CX3CL1 (fractalkine, neurotactin).
Cell Type
Astrocytes, Dendritic cells, Macrophages, Mast cells, Microglia, Monocytes, NK cells, T cells
Biology Area
Cell Adhesion, Cell Biology, Immunology, Innate Immunity, Neuroscience, Neuroscience Cell Markers
Molecular Family
Cytokine/Chemokine Receptors, GPCR
Antigen References

1. Ponzetta A, et al. 2013. J. Immunol. 191:5684.
2. Jacquelin S, et al. 2013. Blood. 122:674.
3. Garcia JA, et al. 2013. J. Immunol. 191:1063.
4. Lee YS, et al. 2013. Cell. 153:413.
5. Shechter R, et al. 2013. Immunity. 38:555.

Gene ID
13051 View all products for this Gene ID
UniProt
View information about CX3CR1 on UniProt.org

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