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Brilliant Violet 421™ anti-mouse CX3CR1 Anti
产品名称：
Brilliant Violet 421™ anti-mouse CX3CR1 Anti
产品类别：
抗体
产品编号：
149023
产品应用：
149023
[价格]
规格 价格 库存
50µg ￥ 4088 1

产品详情

Product Details

Verified Reactivity
Mouse
Antibody Type
Monoclonal
Host Species
Mouse
Immunogen
Mouse CX3CR1-transfected cells
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA).
Preparation
The antibody was purified by affinity chromatography and conjugated with Brilliant Violet 421? under optimal conditions.
Concentration
0.2 mg/ml
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
Application

FC - Quality tested
Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤0.03 ?g per million cells in 100 ?l volume. It is recommended that the reagent be titrated for optimal performance for each application.

Brilliant Violet 421? excites at 405 nm and emits at 421 nm. The standard bandpass filter 450/50 nm is recommended for detection. Brilliant Violet 421? is a trademark of Sirigen Group Ltd.


Learn more about Brilliant Violet?.

This product is subject to proprietary rights of Sirigen Inc. and is made and sold under license from Sirigen Inc. The purchase of this product conveys to the buyer a non-transferable right to use the purchased product for research purposes only. This product may not be resold or incorporated in any manner into another product for resale. Any use for therapeutics or diagnostics is strictly prohibited. This product is covered by U.S. Patent(s), pending patent applications and foreign equivalents.
Excitation Laser
Violet Laser (405 nm)
Application Notes

View more applications data for a different format of this clone in our Scientific Poster Library.

Product Citations
  1. De Biase LM et al. 2017. Neuron. 95(2):341-356 . PubMed
  2. Rosina M, et al. 2022. Cell Metab. 34:533. PubMed
  3. Ren Z, et al. 2021. EMBO Molecular Medicine. :e14059. PubMed
  4. Valencia–Hernandez AM, et al. 2020. Cell Host & Microbe. 27(6):950-962. PubMed
  5. Karlen SJ, et al. 2018. J Neuroinflammation. 15:344. PubMed
  6. Christofi M, et al. 2020. Cell Mol Life Sci. . PubMed
  7. Rao S, et al. 2017. Cell. 168(3):503-516.e12. PubMed
  8. Jtte BB, et al. 2021. iScience. 24(8):102833. PubMed
  9. Burns JC, et al. 2021. Bio Protoc. 11:e4091. PubMed
  10. Prosser A, et al. 2021. Cell Reports. 35(7):109141. PubMed
  11. Doron I, et al. 2021. Cell. 184(4):1017-1031.e14. PubMed
  12. Zhu H, et al. 2021. Cell Metabolism. :. PubMed
  13. Burns JC, et al. 2020. eLife. 9:00. PubMed
  14. Van Winkle JA et al. 2018. Cell host & microbe. 24(5):665-676 . PubMed
  15. Beura LK, et al. 2018. Immunity. 48:327. PubMed
  16. Huang H, et al. 2021. Cell. 184(5):1245-1261.e21. PubMed
  17. Highton AJ, et al. 2019. Wellcome Open Res. 4:78. PubMed
  18. Sema Kurtulus et al. 2018. Immunity. 50(1):181-194 . PubMed
  19. Prosser A, et al. 2021. STAR Protoc. 2:100810. PubMed
  20. Li X, et al. 2018. Cell Host Microbe. 24:847. PubMed
  21. Riopel M, et al. 2019. Mol Metab. 20:89. PubMed
  22. Scheyltjens I, et al. 2022. Nat Protoc. 17:2354. PubMed
RRID
AB_2565706 (BioLegend Cat. No. 149023)

Antigen Details

Structure
G-protein coupled receptor, 7 transmembrane regions, 40 kD.
Distribution

Resident and alternatively activated macrophages (M2), subset of monocytes, dendritic cells (DCs), natural killer cells (NK), subset of memory T cells, mast cells, glial cells, and astrocytes.

Function
Involved in cell recruitment during inflammation, participates in cell adhesion and extravasation from blood vessels, coreceptor for HIV1.
Ligand/Receptor
CX3CL1 (fractalkine, neurotactin).
Cell Type
Astrocytes, Dendritic cells, Macrophages, Mast cells, Microglia, Monocytes, NK cells, T cells
Biology Area
Cell Adhesion, Cell Biology, Immunology, Innate Immunity, Neuroscience, Neuroscience Cell Markers
Molecular Family
Cytokine/Chemokine Receptors, GPCR
Antigen References

1. Ponzetta A, et al. 2013. J. Immunol. 191:5684.
2. Jacquelin S, et al. 2013. Blood. 122:674.
3. Garcia JA, et al. 2013. J. Immunol. 191:1063.
4. Lee YS, et al. 2013. Cell. 153:413.
5. Shechter R, et al. 2013. Immunity. 38:555.

Gene ID
13051 View all products for this Gene ID
UniProt
View information about CX3CR1 on UniProt.org

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