APC anti-mouse CX3CR1 Antibody -上海雅吉生物科技有限公司

规格	价格	库存
25µg	￥ 2086	1

Product Details

Verified Reactivity

Mouse

Antibody Type

Monoclonal

Host Species

Mouse

Immunogen

Mouse CX3CR1-transfected cells

Formulation

Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide; may contain stabilizer.

Preparation

The antibody was purified by affinity chromatography and conjugated with APC under optimal conditions.

Concentration

0.2 mg/ml

Storage & Handling

The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.

Application

FC - Quality tested

Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤0.06 ?g per million cells in 100 ?l volume. It is recommended that the reagent be titrated for optimal performance for each application.

Excitation Laser

Red Laser (633 nm)

Application Notes

View more applications data for a different format of this clone in our Scientific Poster Library.

Additional Product Notes

View more applications data for this product in our Scientific Poster Library.

Product Citations

Liu J, et al. 2017. Mucosal Immunol. 10.1038/mi.2016.139. PubMed
Yu‐Han Chang et al. 2017. Immunity. 47(5):943-958 . PubMed
Kuo PC, et al. 2021. Brain Commun. 3:fcab187. PubMed
Fu R, et al. 2020. Sci Rep. 10:1455. PubMed
Jeong D, et al. 2021. eLife. 0.416666666666667. PubMed
Tuit S, et al. 2019. Cell Rep. 29:1221. PubMed
Anderson CK et al. 2019. Cell Rep. 27(2):537-548 . PubMed
Xu D et al. 2018. Cell. 174(6):1477-1491 . PubMed
Hammond TR, et al. 2019. Immunity. 50:253. PubMed
Mifflin L, et al. 2021. Proc Natl Acad Sci U S A. 118:. PubMed
Leylek R, et al. 2019. Cell Rep. 29:3736. PubMed
Yu X, et al. 2020. Nat Commun. 0.641666667. PubMed
Lee JY, et al. 2020. Nat Commun. 11:2358. PubMed
Frost JN, et al. 2021. Med (N Y). 2:164. PubMed
Favuzzi E, et al. 2021. Cell. 184(15):4048-4063.e32. PubMed
Baomei Wang et al. 2019. Cell reports. 26(6):1614-1626 . PubMed
Hernandez GE, et al. 2022. Nat Cardiovasc Res. 1:67. PubMed
Keerthivasan S, et al. 2021. Immunity. 54(7):1511-1526.e8. PubMed
Shigeta A, et al. 2019. Dev Cell. 48:617. PubMed
Clemente–Casares X, et al. 2017. Immunity. 47:974. PubMed
Korin B, et al. 2020. Sleep. :43. PubMed
Liu SS, et al. 2021. Immunity. :. PubMed
Biagioli M, et al. 2017. J Immunol. 199:718. PubMed
Zhang J, et al. 2020. Cell Metabolism. 31(6):1136-1153. PubMed
Park HJ, et al. 2021. Int J Mol Sci. 22:. PubMed
Mincham KT, et al. 2021. Front Immunol. 11:601494. PubMed

RRID

AB_2564491 (BioLegend Cat. No. 149007) AB_2564492 (BioLegend Cat. No. 149008)

Antigen Details

Structure: G-protein coupled receptor, 7 transmembrane regions, 40 kD.
Distribution: Resident and alternatively activated macrophages (M2), subset of monocytes, dendritic cells (DCs), natural killer cells (NK), subset of memory T cells, mast cells, glial cells, and astrocytes.
Function: Involved in cell recruitment during inflammation, participates in cell adhesion and extravasation from blood vessels, coreceptor for HIV1.
Ligand/Receptor: CX3CL1 (fractalkine, neurotactin).
Cell Type: Astrocytes, Dendritic cells, Macrophages, Mast cells, Microglia, Monocytes, NK cells, T cells
Biology Area: Cell Adhesion, Cell Biology, Immunology, Innate Immunity, Neuroscience, Neuroscience Cell Markers
Molecular Family: Cytokine/Chemokine Receptors, GPCR
Antigen References: 1. Ponzetta A, et al. 2013. J. Immunol. 191:5684.
2. Jacquelin S, et al. 2013. Blood. 122:674.
3. Garcia JA, et al. 2013. J. Immunol. 191:1063.
4. Lee YS, et al. 2013. Cell. 153:413.
5. Shechter R, et al. 2013. Immunity. 38:555.
Gene ID: 13051 View all products for this Gene ID
UniProt: View information about CX3CR1 on UniProt.org

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