Alexa Fluor® 647 anti-mouse CX3CR1 Antibody -上海雅吉生物科技有限公司

规格	价格	库存
25µg	￥ 2226	1

Product Details

Verified Reactivity

Mouse

Antibody Type

Monoclonal

Host Species

Mouse

Immunogen

Mouse CX3CR1-transfected cells

Formulation

Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide; may contain stabilizer.

Preparation

The antibody was purified by affinity chromatography and conjugated with Alexa Fluor? 647 under optimal conditions.

Concentration

0.5 mg/ml

Storage & Handling

The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.

Application

FC - Quality tested

Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤0.125 ?g per million cells in 100 ?l volume. It is recommended that the reagent be titrated for optimal performance for each application.

* Alexa Fluor? 647 has a maximum emission of 668 nm when it is excited at 633 nm / 635 nm.

Alexa Fluor? and Pacific Blue? are trademarks of Life Technologies Corporation.

View full statement regarding label licenses

Excitation Laser

Red Laser (633 nm)

Application Notes

View more applications data for a different format of this clone in our Scientific Poster Library.

Product Citations

Filipello F et al. 2018. Immunity. 48(5):979-991 . PubMed
Ding X, et al. 2021. Nat Commun. 12:2030. PubMed
Tanner MA, et al. 2021. Am J Physiol Heart Circ Physiol. 321:H633. PubMed
Bhattacherjee A, et al. 2019. Commun Biol. 2:450. PubMed
Lehrman EK et al. 2018. Neuron. 100(1):120-134 . PubMed
Gentek R, et al. 2018. Immunity. 48:1160. PubMed
Sun X, et al. 2020. Cell Metabolism. 31(1):189-206.e8.. PubMed
Seidman JS, et al. 2020. Immunity. 52(6):1057-1074. PubMed

RRID

AB_2564272 (BioLegend Cat. No. 149003) AB_2564273 (BioLegend Cat. No. 149004)

Antigen Details

Structure: G-protein coupled receptor, 7 transmembrane regions, 40 kD.
Distribution: Resident and alternatively activated macrophages (M2), subset of monocytes, dendritic cells (DCs), natural killer cells (NK), subset of memory T cells, mast cells, glial cells, and astrocytes.
Function: Involved in cell recruitment during inflammation, participates in cell adhesion and extravasation from blood vessels, coreceptor for HIV1.
Ligand/Receptor: CX3CL1 (fractalkine, neurotactin).
Cell Type: Astrocytes, Dendritic cells, Macrophages, Mast cells, Microglia, Monocytes, NK cells, T cells
Biology Area: Cell Adhesion, Cell Biology, Immunology, Innate Immunity, Neuroscience, Neuroscience Cell Markers
Molecular Family: Cytokine/Chemokine Receptors, GPCR
Antigen References: 1. Ponzetta A, et al. 2013. J. Immunol. 191:5684.
2. Jacquelin S, et al. 2013. Blood. 122:674.
3. Garcia JA, et al. 2013. J. Immunol. 191:1063.
4. Lee YS, et al. 2013. Cell. 153:413.
5. Shechter R, et al. 2013. Immunity. 38:555.
Gene ID: 13051 View all products for this Gene ID
UniProt: View information about CX3CR1 on UniProt.org

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