Purified anti-human CD328 (Siglec-7) Antibody -上海雅吉生物科技有限公司

规格	价格	库存
100µg	￥ 3122	1

规格

价格

库存

100µg

￥ 3122

Product Details

Verified Reactivity

Human

Antibody Type

Monoclonal

Host Species

Mouse

Immunogen

Siglec-7 3T3 transfected cells

Formulation

Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.

Preparation

The antibody was purified by affinity chromatography.

Concentration

0.5 mg/ml

Storage & Handling

The antibody solution should be stored undiluted between 2°C and 8°C.

Application

FC - Quality tested
IP, Block - Reported in the literature, not verified in house

Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤0.5 ?g per million cells in 100 ?l volume. It is recommended that the reagent be titrated for optimal performance for each application.

Application Notes

Additional reported applications (for the relevant formats) include: Blocking².

Application References (PubMed link indicates BioLegend citation)

Nicoll G, et al. 1999. J. Biol Chem. 274:34089.
Hudak J, et al. 2014. Nat. Chem Biol. 10:69–75.

RRID

AB_2189411 (BioLegend Cat. No. 347702)

Antigen Details

Structure: Type I transmembrane protein, Siglec family member, 75 kD
Distribution: Monocytes, NK cells
Function: Inhibitory receptor of NK cells
Interaction: After tyrosine phosphorylation interacts with PTPN6 and SHP-1
Ligand/Receptor: Sialylated glycans (with α,8 disialyl and α2,6 sialyl residues)
Bioactivity: Inhibition of signal transduction by recruiting cytoplasmic phosphatases
Cell Type: Monocytes, NK cells
Biology Area: Immunology
Molecular Family: Adhesion Molecules, CD Molecules, Siglec Molecules
Antigen References: 1. Avril T, et al. 2006. Infect Immun. 74:4133.
2. Avril T, et al. 2006. J. Leukoc. Biol. 80:787.
3. Orr SJ, et al. 2007. J. Biol Chem. 282:3418.
4. Brunetta E, et al. 2009. Blood 114:3822.
Gene ID: 27036 View all products for this Gene ID
UniProt: View information about CD328 on UniProt.org

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