Alexa Fluor® 594 anti-human CD44 variant 9 (CD
- 产品名称：
- Alexa Fluor® 594 anti-human CD44 variant 9 (CD
- 产品类别：
- 抗体
- 产品编号：
- 394405
- 产品应用：
- 394405
- Verified Reactivity
- Human
- Antibody Type
- Monoclonal
- Host Species
- Rat
- Immunogen
- Human CD44v8-10 transfected cells
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
- Preparation
- The antibody was purified by affinity chromatography and conjugated with Alexa Fluor? 594 under optimal conditions.
- Concentration
- 0.5 mg/ml
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
- Application
-
IHC-P - Quality tested
- Recommended Usage
Each lot of this antibody is quality control tested by formalin-fixed paraffin-embedded immunohistochemical staining. For immunohistochemistry, a concentration range of 5.0 - 10 ?g/ml is suggested. It is recommended that the reagent be titrated for optimal performance for each application.
* Alexa Fluor? 594 has an excitation maximum of 590 nm, and a maximum emission of 617 nm.
Alexa Fluor? and Pacific Blue? are trademarks of Life Technologies Corporation.
View full statement regarding label licenses - Application Notes
Additional reported applications (for the relevant formats) include: immunohistochemical staining of frozen tissue sections3.
- Application References
(PubMed link indicates BioLegend citation) -
- Kakehashi, A., et al. 2016. Cancer Sci. 107: 609. (IHC-P)
- Aso T, et al. 2015. PLoS One. 10: e0116596. (IHC-P)
- Yoshikawa M, et al. 2013. Cancer Res. 73: 1855. (IHC-F)
- Ishimoto T, et al. 2011. Cancer Cell. 387-400. (IHC-P)
- RRID
- AB_2783305 (BioLegend Cat. No. 394405) AB_2783306 (BioLegend Cat. No. 394406)
- Distribution
-
Cancer stem cells, epithelial-type carcinomas, subset of monocytes, subset of lymphocytes.
- Function
- Role in tumor initiation and maintenance and metastasis of cancer cells, Interacts with the glutamate-cystine transporter xCT, increasing reduced glutathione and contributing to the ROS resistance of cancer cells.
- Cell Type
- Epithelial cells, Lymphocytes, Monocytes, Neutrophils
- Biology Area
- Cancer Biomarkers, Cell Biology, Immunology
- Molecular Family
- Adhesion Molecules, CD Molecules
- Antigen References
-
- Hagiwara M, et al. 2018. BMC Cancer. 18:113
- Matsumoto T, et al. 2017. Oncogenesis. 6:397
- Bertaux-Skeirik N, et al. 2017. J. Pathol. 242:463
- Kodama H, et al. 2017. Br. J. Cancer. 116:186
- Gene ID
- 960 View all products for this Gene ID
- UniProt
- View information about CD44v9 on UniProt.org
