PE anti-human CD317 (BST2, Tetherin) Antibody -上海雅吉生物科技有限公司

规格	价格	库存
25tests	￥ 2142	1

Product Details

Verified Reactivity

Human, Cynomolgus, Rhesus

Reported Reactivity

African Green, Baboon, Pigtailed Macaque

Antibody Type

Monoclonal

Host Species

Mouse

Formulation

Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)

Preparation

The antibody was purified by affinity chromatography and conjugated with PE under optimal conditions.

Concentration

Lot-specific (to obtain lot-specific concentration, please enter the lot number in our Concentration and Expiration Lookup or Certificate of Analysis online tools.)

Storage & Handling

The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.

Application

FC - Quality tested

Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 ?l per million cells in 100 ?l staining volume or 5 ?l per 100 ?l of whole blood.

Excitation Laser

Blue Laser (488 nm)
Green Laser (532 nm)/Yellow-Green Laser (561 nm)

Application References (PubMed link indicates BioLegend citation)

Ishikawa J, et al. 1995. Genomics 26:527.
Miyagi E, et al. 2011. J. Virol. 85:11981. PubMed
Yokoyama T, et al. 2013. Int. J. Cancer. 132: 472. (FC) PubMed

Product Citations

Fukuma A, et al. 2013. PLoS One. 8:61530.. PubMed
Soday L, et al. 2021. Frontiers in Immunology. 12:600056. PubMed
Martrus G, et al. 2016. J Virol. 90: 9018 - 9028. PubMed
Bellini N, et al. 2022. iScience. 25:105234. PubMed
Zadeh VR, et al. 2020. J Gen Virol. 101:573. PubMed
Hamilton J, et al. 2015. J Immunol. 194:5022. PubMed
Rai MA, et al. 2020. Retrovirology. 17:35. PubMed
Wang X, et al. 2022. J Immunol. 208:396. PubMed
Urata S, et al. 2018. PLoS Pathog. 14:e1007172. PubMed
Naamati A, et al. 2019. Elife. 8:e41431. PubMed
Lau D, et al. 2011. J Virol. 85:9834. PubMed
van Stigt Thans T, et al. 2020. Journal of Virology. 93(20):e00719-19.. PubMed
Ma T, et al. 2016. Sci Rep. 6:34752. PubMed
Thippeshappa R, et al. 2013. J Virol. 87:6678. PubMed

RRID

AB_10567247 (BioLegend Cat. No. 348405) AB_10564402 (BioLegend Cat. No. 348406)

Disclaimer

This product is manufactured and sold under a license and covered by a number of issued patents.?Users who intend to file a patent relating to the use of this product or who intend to develop therapeutic use of this antibody are required to report to Biolegend in advance.

Antigen Details

Structure: Type II transmembrane, GPI-anchored protein, 29-33 kD
Distribution: Dendritic cells, plasma cells, B lymphoblast cells, monocytes, granulocytes, T cells, NK cells, stromal cells
Function: Regulate B cell growth, inhibit cytokine production, retain progeny virons on the surface of infected cells
Ligand/Receptor: ILT7 (CD85g)
Cell Type: B cells, Dendritic cells, Granulocytes, Monocytes, NK cells, Plasma cells, T cells
Biology Area: Costimulatory Molecules, Immunology, Innate Immunity
Molecular Family: Adhesion Molecules, CD Molecules
Antigen References: 1. Sugamata OT, et al. 1999. Biochem. Bioph. Res. Co. 258:583.
2. Neil SJ, et al. 2008. Nature 451:425.
3. Fitzpatrick K, et al. 2010. PLoS Pathog. 6:e1000701.
4. Azuma KS, et al. 2008. Cancer Sci. 99:2461.
5. Cao W, et al. 2009. J. Exp. Med. 206:1603.
6. Zola H, et al. 2007. Leukocyte and Stromal Cell Molecules:The CD Markers.
Gene ID: 684 View all products for this Gene ID
UniProt: View information about CD317 on UniProt.org

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