APC anti-human CD2 Antibody
- 产品名称：
- APC anti-human CD2 Antibody
- 产品类别：
- 抗体
- 产品编号：
- 300213
- 产品应用：
- 300213
[价格]
| 规格 |
价格 |
库存 |
| 25tests |
￥ 1624 |
1 |
- Verified Reactivity
- Human, Cynomolgus, Rhesus
- Reported Reactivity
- African Green, Baboon, Capuchin Monkey, Chimpanzee, Pigtailed Macaque, Pig
- Antibody Type
- Monoclonal
- Host Species
- Mouse
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
- Preparation
- The antibody was purified by affinity chromatography and conjugated with APC under optimal conditions.
- Concentration
- Lot-specific (to obtain lot-specific concentration, please enter the lot number in our Concentration and Expiration Lookup or Certificate of Analysis online tools.)
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
- Application
-
FC - Quality tested
- Recommended Usage
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 ?l per million cells in 100 ?l staining volume or 5 ?l per 100 ?l of whole blood.
- Excitation Laser
- Red Laser (633 nm)
- Application Notes
Additional reported applications (for the relevant formats) include: immunohistochemical staining of acetone-fixed frozen tissue sections6 and blocking of T cell activation2. The Ultra-LEAF? purified antibody (Endotoxin <0.1 EU/?g, Azide-Free, 0.2 ?m filtered) is recommended for functional assays (Cat. Nos. 300239 & 300240).
- Application References
(PubMed link indicates BioLegend citation) -
- Knapp W, et al. Eds. 1989. Leucocyte Typing IV. Oxford University Press. New York.
- Aversa G, et al. 1987. Transplant. Proc. 19:277. (Block)
- Zaretsky AG, et al. 2009. J. Exp Med. 206:991. (IHC) PubMed
- Perona-Wright G, et al. 2010. Nat. Immunol. 11:520. (FC) PubMed
- Thummler K, et al. 2010. J. Leukoc. Biol. 88:1041.
- Kap Y, et al. 2009. J. Histochem. Cytochem. 57:1159. (IHC)
- Yoshino N, et al. 2000. Exp. Anim. (Tokyo) 49:97. (FC)
- Product Citations
-
- Mancuso RV, et al. 2020. British Journal of Pharmacology. 177(12):2696-2711.. PubMed
- Matsumoto R, et al. 2021. Front Pharmacol. 12:715752. PubMed
- Delacher M, et al. 2021. Immunity. 54(4):702-720.e17. PubMed
- Hayatsu N et al. 2017. Immunity. 47(2):268-283 . PubMed
- Beatson RE, et al. 2021. Cell Rep Med. 2:100473. PubMed
- Divito SJ, et al. 2020. J Clin Invest. 130:4624. PubMed
- Kawakami R, et al. 2021. Immunity. 54(5):947-961.e8. PubMed
- Ng SY, et al. 2018. Nat Commun. 9:2024. PubMed
- Kamiya T, et al. 2018. Blood Adv. 2:517. PubMed
- He Y, et al. 2020. J Hematol Oncol. 0.607638889. PubMed
- Bennstein SB, et al. 2020. eLife. 9:e55232.. PubMed
- RRID
- AB_10900259 (BioLegend Cat. No. 300213) AB_10895925 (BioLegend Cat. No. 300214)
- Structure
- Ig superfamily, type I transmembrane glycoprotein, 50 kD
- Distribution
-
T cells, NK cells, thymocytes, and thymic B cell subsets
- Function
- T cell activation, adhesion
- Ligand/Receptor
- CD58 (LFA-3), CD48, CD59, CD15
- Cell Type
- B cells, NK cells, T cells, Thymocytes
- Biology Area
- Costimulatory Molecules, Immunology
- Molecular Family
- Adhesion Molecules, CD Molecules
- Antigen References
-
1. Bell G, et al. 1995. J. Immunol. 155:2805.
2. Bierer B, et al. 1989. Annu. Rev. Immunol. 7:579.
3. Moingeon P, et al. 1989. Immunol. Rev. 111:111.
- Gene ID
- 914 View all products for this Gene ID
- UniProt
- View information about CD2 on UniProt.org
