Purified anti-rat CD62P (P-selectin) Antibody
- 产品名称：
- Purified anti-rat CD62P (P-selectin) Antibody
- 产品类别：
- 抗体
- 产品编号：
- 206002
- 产品应用：
- 206002
- Verified Reactivity
- Rat
- Antibody Type
- Monoclonal
- Host Species
- Mouse
- Immunogen
- Thrombin activated rat platelets
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
- Preparation
- The antibody was purified by affinity chromatography.
- Concentration
- 0.5 mg/ml
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C.
- Application
-
FC - Quality tested
ICC, IHC-F, ELISA - Reported in the literature, not verified in house
- Recommended Usage
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 1.0 ?g per million cells in 100 ?l volume. It is recommended that the reagent be titrated for optimal performance for each application.
- Application Notes
Additional reported applications (for the relevant formats of this clone) include: immunofluorescence staining2, immunohistochemistry of acetone-fixed frozen sections2, and ELISA capture3.
- Application References
(PubMed link indicates BioLegend citation) -
- Walter UM, et al. 1997. Immunology. 92:290. (Blocking function)
- Morise Z, et al. 1998. Am. J. Physiol. 274:G246. (IF, IHC - frozen)
- Walter UM, et al. 1997. Hybridoma. 16:249. (ELISA capture)
- Product Citations
-
- Zhao W, et al. 2021. J Thromb Haemost. 19:3113. PubMed
- RRID
- AB_2564112 (BioLegend Cat. No. 206002)
- Structure
- Type I transmembrane glycoprotein, 140 kD
- Distribution
-
Activated platelets, megakaryocytes, and endothelial cells.
- Function
- Adhesion, neutrophil rolling, platelet-neutrophil, and platelet-monocyte interactions.
- Ligand/Receptor
- CD162 (PSGL-1), CD24, and sialylated Lewis X
- Cell Type
- Endothelial cells, Megakaryocytes, Platelets
- Biology Area
- Cell Adhesion, Cell Biology, Immunology, Innate Immunity, Neuroscience, Synaptic Biology
- Molecular Family
- Adhesion Molecules, CD Molecules
- Antigen References
-
1. McEver R, et al. 1995. J. Biol. Chem. 270:11025.
2. Varki A. 1994. Proc. Natl. Acad. Sci. USA 91:7390.
- Gene ID
- 25651 View all products for this Gene ID
- UniProt
- View information about CD62P on UniProt.org
