PE anti-mouse CD51 Antibody
- 产品名称：
- PE anti-mouse CD51 Antibody
- 产品类别：
- 抗体
- 产品编号：
- 104105
- 产品应用：
- 104105
- Verified Reactivity
- Mouse
- Antibody Type
- Monoclonal
- Host Species
- Rat
- Immunogen
- BALB/c mouse IL-2-activated killer (LAK) cells
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
- Preparation
- The antibody was purified by affinity chromatography, and conjugated with PE under optimal conditions.
- Concentration
- 0.2 mg/ml
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
- Application
-
FC - Quality tested
- Recommended Usage
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤1.0 ?g per million cells in 100 ?l volume. It is recommended that the reagent be titrated for optimal performance for each application.
- Excitation Laser
- Blue Laser (488 nm)
Green Laser (532 nm)/Yellow-Green Laser (561 nm)
- Application Notes
Additional reported applications (for the relevant formats) include: immunoprecipitation1, and blocking1-3 of CD51 adhesion and LAK cell cytotoxicity. The Ultra-LEAF? purified antibody (Endotoxin <0.01 EU/?g, Azide-Free, 0.2 ?m filtered) is recommended for functional assays (Cat. Nos. 104109 & 104110).
- Application References
(PubMed link indicates BioLegend citation) -
- Takahashi K, et al. 1990. J. Immunol. 145:4371. (IP Block)
- Narumiya S, et al. 1994. Int. Immunol. 6:139. (Block)
- Piali L, et al. 1995. J. Cell Biol. 130:451. (Block)
- Delpino MV, et al. 2012. J. Leukoc Biol 91:285. PubMed.
- Product Citations
-
- Barrett N, et al. 2016. Cell Rep. 16: 1039-1054. PubMed
- Weng L, et al. 2016. Sci Rep. 6:38632. PubMed
- Schloss MJ, et al. 2022. Nat Immunol. 23:605. PubMed
- Hu X, et al. 2016. Nat Commun. 7:13095. PubMed
- Minutti CM, et al. 2019. Immunity. 50:645. PubMed
- Kakiuchi K, et al. 2014. Biol Reprod. 90:82. PubMed
- Leimkühler NB, et al. 2020. Cell Stem Cell. 28:637. PubMed
- Mann M, et al. 2018. Cell Rep. 25:2992. PubMed
- Revenco T, et al. 2019. Cell Rep. 29:1458. PubMed
- Bai Y, et al. 2021. Front Cell Dev Biol. 9:730095. PubMed
- Derecka M, et al. 2020. Nat Immunol. 261:21. PubMed
- Srivastava S, et al. 2019. Cancer Cell. 35:489. PubMed
- Morimoto A, et al. 2021. Nat Commun. 12:2136. PubMed
- Russler-Germain EV, et al. 2021. Elife. 10:. PubMed
- Kenswil KJG, et al. 2021. Cell Stem Cell. 28(4):653-670.e11. PubMed
- Horiguchi H, et al. 2019. Genes Dev. 33:1641. PubMed
- Lin C, et al. 2022. Nat Commun. 13:6869. PubMed
- Delpino M, et al. 2012. J Leukoc Biol. 91:285. PubMed
- Krohn-Grimberghe M, et al. 2020. Nat Biomed Eng. 1076:4. PubMed
- Nowlan B, et al. 2019. Haematologica. 105:71. PubMed
- Pastushenko I, et al. 2020. Nature. 589:448. PubMed
- Chandrakanthan V, et al. 2016. Proc Natl Acad Sci U S A. 113: 2306-2315. PubMed
- Gaylo‐Moynihan A et al. 2019. Immunity. 51(2):298-309 . PubMed
- Malenica I, et al. 2021. Nat Commun. 12:5209. PubMed
- Young K, et al. 2021. Cell Stem Cell. . PubMed
- Guarnerio J, et al. 2018. Nat Commun. 9:66. PubMed
- RRID
- AB_313074 (BioLegend Cat. No. 104105) AB_2129493 (BioLegend Cat. No. 104106)
- Structure
- Integrin family, associates with integrins β1, β3, β5 or β6, 140 kD
- Distribution
-
Activated T cells, polymorphonuclear granulocytes, blastocysts, osteoclasts
- Function
- Adhesion
- Ligand/Receptor
- Fibronectin, fibrinogen, vitronectin, thrombspondin, von Willebrand factor, and CD31
- Cell Type
- Granulocytes, Mesenchymal Stem Cells, Osteoclasts, T cells
- Biology Area
- Angiogenesis, Cell Adhesion, Cell Biology, Costimulatory Molecules, Immunology, Innate Immunity, Stem Cells
- Molecular Family
- Adhesion Molecules, CD Molecules
- Antigen References
-
1. Barclay AN, et al. 1997. The Leukocyte Antigen FactsBook Academic Press.
2. Maxfield SR, et al. 1989. J. Exp. Med. 169:2173.
3. Piali L, et al. 1995. J. Cell Biol. 130:451.
- Gene ID
- 16410 View all products for this Gene ID
- UniProt
- View information about CD51 on UniProt.org
