Purified anti-mouse CD279 (PD-1) Antibody
- 产品名称：
- Purified anti-mouse CD279 (PD-1) Antibody
- 产品类别：
- 抗体
- 产品编号：
- 109101
- 产品应用：
- 109101
- Verified Reactivity
- Mouse
- Antibody Type
- Monoclonal
- Host Species
- Rat
- Immunogen
- Mouse PD-1 transfected BHK cells
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
- Preparation
- The antibody was purified by affinity chromatography.
- Concentration
- 0.5 mg/ml
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C.
- Application
-
FC - Quality tested
IHC-F - Verified
- Recommended Usage
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤0.25 ?g per million cells in 100 ?l volume. It is recommended that the reagent be titrated for optimal performance for each application.
- Application Notes
The RMP1-30 antibody does not block the binding of PD-1 to B7-H1 and B7-DC1.
- Application References
(PubMed link indicates BioLegend citation) -
- Matsumoto K, et al. 2004. J. Immunol. 172:2530.
- Raimondi G, et al. 2006. J. Immunol. 176:2808. (FC) PubMed
- King IL, et al. 2009. J. Exp Med 206:1001. (FC) PubMed
- Product Citations
-
- Horton BL, et al. 2018. Cancer Immunol Res. 6:14. PubMed
- Abboud G, et al. 2018. Front Immunol. 9:1973. PubMed
- Brown IK, et al. 2021. PLoS Pathog. 17:e1009602. PubMed
- Park GY, et al. 2020. Immune Netw. e43:20. PubMed
- Kenna T, et al. 2008. Blood. 111:2091. PubMed
- Zander R, et al. 2017. Cell Rep.. 10.1016/j.celrep.2017.10.077. PubMed
- Raimondi G, et al. 2006. J Immunol. 176:2808. PubMed
- Stelekati E, et al. 2018. Cell Rep. 2.445833333. PubMed
- Xu W, et al. 2021. Immunity. 54(3):526-541.e7. PubMed
- Kang SH, et al. 2018. Oncoimmunology. 8:e1515057. PubMed
- RRID
- AB_313418 (BioLegend Cat. No. 109101)
- Structure
- Ig superfamily, 50-55 kD
- Distribution
-
Subset of double negative thymocytes, activated T and B cells
- Function
- Lymphocyte clonal selection, peripheral tolerance
- Ligand/Receptor
- PD-L1 (B7-H1), PD-L2
- Cell Type
- B cells, T cells, Thymocytes, Tregs
- Biology Area
- Apoptosis/Tumor Suppressors/Cell Death, Cancer Biomarkers, Cell Biology, Immunology, Inhibitory Molecules
- Molecular Family
- CD Molecules, Immune Checkpoint Receptors
- Antigen References
-
1. Barclay A, et al. 1997. The Leukocyte Antigen FactsBook Academic Press.
2. Agata Y, et al. 1996. Int. Immunol. 8:765.
3. Nishimura H, et al. 2001. Science 291:319.
4. Ishida Y, et al. 1992. EMBO J. 11:3887.
- Gene ID
- 18566 View all products for this Gene ID
- UniProt
- View information about CD279 on UniProt.org
