Purified anti-mouse CD279 (PD-1) (Maxpar® Read-上海雅吉生物科技有限公司

规格	价格	库存
100µg	￥ 2226	1

Product Details

Verified Reactivity

Mouse

Antibody Type

Monoclonal

Host Species

Rat

Immunogen

Mouse PD-1 transfected BHK cells

Formulation

Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and EDTA.

Preparation

The antibody was purified by affinity chromatography.

Concentration

1.0 mg/ml

Storage & Handling

The antibody solution should be stored undiluted between 2°C and 8°C.

Application

FC - Quality tested
CyTOF? - Verified

Recommended Usage

This product is suitable for use with the?Maxpar? Metal Labeling Kits.?For metal labeling using Maxpar? Ready antibodies,?proceed directly to the step to Partially Reduce the Antibody by adding 100 ?l of Maxpar? Ready antibody to 100 ?l of 4 mM TCEP-R in a 50 kDa filter and continue with the protocol. Always refer to the latest version of Maxpar? User Guide when conjugating Maxpar? Ready antibodies.

Application Notes

The RMP1-30 antibody does not block the binding of PD-1 to B7-H1 and B7-DC¹.

Additional Product Notes

Maxpar? is a registered trademark of Standard BioTools Inc.

Application References (PubMed link indicates BioLegend citation)

Matsumoto K, et al. 2004. J. Immunol. 172:2530.
Raimondi G, et al. 2006. J. Immunol. 176:2808. (FC) PubMed
King IL, et al. 2009. J. Exp Med 206:1001. (FC) PubMed

Product Citations

McDonald B, et al. 2020. Cell Host Microbe. 28(5):660-668.e4. PubMed

RRID

AB_2563735 (BioLegend Cat. No. 109113)

Antigen Details

Structure: Ig superfamily, 50-55 kD
Distribution: Subset of double negative thymocytes, activated T and B cells
Function: Lymphocyte clonal selection, peripheral tolerance
Ligand/Receptor: PD-L1 (B7-H1), PD-L2
Cell Type: B cells, T cells, Thymocytes, Tregs
Biology Area: Apoptosis/Tumor Suppressors/Cell Death, Cancer Biomarkers, Cell Biology, Immunology, Inhibitory Molecules
Molecular Family: CD Molecules, Immune Checkpoint Receptors
Antigen References: 1. Barclay A, et al. 1997. The Leukocyte Antigen FactsBook Academic Press.
2. Agata Y, et al. 1996. Int. Immunol. 8:765.
3. Nishimura H, et al. 2001. Science 291:319.
4. Ishida Y, et al. 1992. EMBO J. 11:3887.
Gene ID: 18566 View all products for this Gene ID
UniProt: View information about CD279 on UniProt.org

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