PE anti-mouse CD279 (PD-1) Antibody
- 产品名称：
- PE anti-mouse CD279 (PD-1) Antibody
- 产品类别：
- 抗体
- 产品编号：
- 109103
- 产品应用：
- 109103
- Verified Reactivity
- Mouse
- Antibody Type
- Monoclonal
- Host Species
- Rat
- Immunogen
- Mouse PD-1 transfected BHK cells
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
- Preparation
- The antibody was purified by affinity chromatography, and conjugated with PE under optimal conditions.
- Concentration
- 0.2 mg/ml
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
- Application
-
FC - Quality tested
- Recommended Usage
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤1.0 ?g per million cells in 100 ?l volume. It is recommended that the reagent be titrated for optimal performance for each application.
- Excitation Laser
- Blue Laser (488 nm)
Green Laser (532 nm)/Yellow-Green Laser (561 nm)
- Application Notes
The RMP1-30 antibody does not block the binding of PD-1 to B7-H1 and B7-DC1.
- Application References
(PubMed link indicates BioLegend citation) -
- Matsumoto K, et al. 2004. J. Immunol. 172:2530.
- Raimondi G, et al. 2006. J. Immunol. 176:2808. (FC) PubMed
- King IL, et al. 2009. J. Exp Med 206:1001. (FC) PubMed
- Product Citations
-
- Bradley CP et al. 2017. Cell host & microbe. 22(5):697-704 . PubMed
- Zhao J, et al. 2021. Emerg Microbes Infect. 10:913. PubMed
- Shimizu K, et al. 2020. Molecular Cell. 77(5):937-950.e6.. PubMed
- Bally AP, et al. 2017. J Immunol. 198:205. PubMed
- Vanderleyden I, et al. 2020. Cell Rep. 30:611. PubMed
- Barrow AD et al. 2018. Cell. 172(3):534-548 . PubMed
- Tata A, et al. 2021. Oncoimmunology. 10:1933808. PubMed
- Bally A, et al. 2015. J Immunol. 194:4545. PubMed
- Christian LS, et al. 2021. Cell Reports. 35(6):109118. PubMed
- Liu QZ, et al. 2018. Front Immunol. 1.131944444. PubMed
- Quatrini L, et al. 2018. Nat Immunol. 19:954. PubMed
- Chow MT et al. 2019. Immunity. 50(6):1498-1512 . PubMed
- Mitchell JE, et al. 2021. Cell Reports. 35(2):108966. PubMed
- Zhuang Z, et al. 2021. J Exp Med. 218:00:00. PubMed
- Nicolay N, et al. 2016. Sci Rep. 6: 26645. PubMed
- Uchil PD et al. 2018. Cell host & microbe. 25(1):87-100 . PubMed
- An J, et al. 2022. iScience. 25:103570. PubMed
- Zeng W, et al. 2016. Sci Rep. 6:36560. PubMed
- Snell LM, et al. 2018. Immunity. 49:678. PubMed
- Zhang B, et al. 2021. Nat Biomed Eng. 5:1288. PubMed
- Karnowski A, et al. 2012. J Exp Med. 209:2049. PubMed
- Weaver JD, et al. 2022. Oncoimmunology. 11:2141007. PubMed
- St Clair JB, et al. 2017. PLoS One. 12:e0170556. PubMed
- Park S, et al. 2014. J Leukoc Biol. 95:621. PubMed
- Lu X, et al. 2015. J Immunol. 194:2011. PubMed
- Li H, et al. 2020. Nature. 584:274. PubMed
- Chatterjee S et al. 2017. Cell metabolism. 27(1):85-100 . PubMed
- Sun M, et al. 2021. J Immunother Cancer. 9:. PubMed
- Huang J, et al. 2014. J Immunol. 192:1972. PubMed
- Zhao Y et al. 2018. Cell reports. 24(2):379-390 . PubMed
- Nasarre P, et al. 2021. Cancers (Basel). 13: . PubMed
- Celis‐Gutierrez J et al. 2019. Cell Rep. 27(11):3315-3330 . PubMed
- Ding Z, et al. 2017. Sci Rep. 10.1038/s41598-017-12488-z. PubMed
- Timilshina M, et al. 2020. Cell Reports. 27(10):2948-2961.e7.. PubMed
- Puleston D, et al. 2014. Elife. 3:3706. PubMed
- Park H, et al. 2012. Cell Immunol. 278:76. PubMed
- RRID
- AB_313420 (BioLegend Cat. No. 109103) AB_313421 (BioLegend Cat. No. 109104)
- Structure
- Ig superfamily, 50-55 kD
- Distribution
-
Subset of double negative thymocytes, activated T and B cells
- Function
- Lymphocyte clonal selection, peripheral tolerance
- Ligand/Receptor
- PD-L1 (B7-H1), PD-L2
- Cell Type
- B cells, T cells, Thymocytes, Tregs
- Biology Area
- Apoptosis/Tumor Suppressors/Cell Death, Cancer Biomarkers, Cell Biology, Immunology, Inhibitory Molecules
- Molecular Family
- CD Molecules, Immune Checkpoint Receptors
- Antigen References
-
1. Barclay A, et al. 1997. The Leukocyte Antigen FactsBook Academic Press.
2. Agata Y, et al. 1996. Int. Immunol. 8:765.
3. Nishimura H, et al. 2001. Science 291:319.
4. Ishida Y, et al. 1992. EMBO J. 11:3887.
- Gene ID
- 18566 View all products for this Gene ID
- UniProt
- View information about CD279 on UniProt.org
