KIRAVIA Blue 520™ anti-mouse CD279 (PD-1) An
- 产品名称：
- KIRAVIA Blue 520™ anti-mouse CD279 (PD-1) An
- 产品类别：
- 抗体
- 产品编号：
- 109129
- 产品应用：
- 109129
- Verified Reactivity
- Mouse
- Antibody Type
- Monoclonal
- Host Species
- Rat
- Immunogen
- Mouse PD-1 transfected BHK cells
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide
- Preparation
- The antibody was purified by affinity chromatography and conjugated with KIRAVIA Blue 520? under optimal conditions.
- Concentration
- 0.2 mg/mL
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
- Application
-
FC - Quality tested
- Recommended Usage
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 1.0 ?g per million cells in 100 ?L volume. It is recommended that the reagent be titrated for optimal performance for each application.
* KIRAVIA Blue 520? has an excitation maximum of 495 nm, and a maximum emission of 520 nm.
KIRAVIA Blue? 520 is a trademark of Sony. This product is subject to proprietary rights of Sony and is made and sold under license from Sony Corporation. This product is covered by U.S. Patent(s), pending patent applications and foreign equivalents.
Sony and the Sony logo are registered trademarks of Sony Corporation. - Excitation Laser
- Blue Laser (488 nm)
- Application Notes
The RMP1-30 antibody does not block the binding of PD-1 to B7-H1 and B7-DC1.
- Application References
(PubMed link indicates BioLegend citation) -
- Matsumoto K, et al. 2004. J. Immunol. 172:2530.
- Raimondi G, et al. 2006. J. Immunol. 176:2808. (FC) PubMed
- King IL, et al. 2009. J. Exp Med 206:1001. (FC) PubMed
- RRID
- AB_2924449 (BioLegend Cat. No. 109129) AB_2924449 (BioLegend Cat. No. 109130)
- Structure
- Ig superfamily, 50-55 kD
- Distribution
-
Subset of double negative thymocytes, activated T and B cells
- Function
- Lymphocyte clonal selection, peripheral tolerance
- Ligand/Receptor
- PD-L1 (B7-H1), PD-L2
- Cell Type
- B cells, T cells, Thymocytes, Tregs
- Biology Area
- Apoptosis/Tumor Suppressors/Cell Death, Cancer Biomarkers, Cell Biology, Immunology, Inhibitory Molecules
- Molecular Family
- CD Molecules, Immune Checkpoint Receptors
- Antigen References
-
1. Barclay A, et al. 1997. The Leukocyte Antigen FactsBook Academic Press.
2. Agata Y, et al. 1996. Int. Immunol. 8:765.
3. Nishimura H, et al. 2001. Science 291:319.
4. Ishida Y, et al. 1992. EMBO J. 11:3887.
- Gene ID
- 18566 View all products for this Gene ID
- UniProt
- View information about CD279 on UniProt.org
