Purified anti-mouse DLL3 Antibody
- 产品名称:
- Purified anti-mouse DLL3 Antibody
- 产品类别:
- 抗体
- 产品编号:
- 154002
- 产品应用:
- 154002
- Verified Reactivity
- Mouse
- Antibody Type
- Monoclonal
- Host Species
- Rat
- Immunogen
- Mouse DLL3-FC
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
- Preparation
- The antibody was purified by affinity chromatography.
- Concentration
- 0.5 mg/ml
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C.
- Application
-
ICFC -?Quality tested
- Recommended Usage
Each lot of this antibody is quality control tested by intracellular immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤0.06 ?g per million cells in 100 ?l volume. It is recommended that the reagent be titrated for optimal performance for each application.
- Application Notes
Staining for DLL3 using clone RMD3-13 requires fixation and permeabilization. This clone does not work for surface DLL3 staining.
- Application References
(PubMed link indicates BioLegend citation) -
- Murata A, et al. 2014. PLoS One. 9:e108535.
- RRID
- AB_2728210 (BioLegend Cat. No. 154002)
- Structure
- Type I transmembrane protein with a DSL domain and 6 or 8 EGF-like repeats
- Distribution
-
Thymus, Brain
- Function
- Embryogenesis, maintaining tissue homeostasis
- Interaction
- Inhibition of Notch downstream signaling
- Ligand/Receptor
- Notch 1
- Antigen References
-
1. Deng S M,?et al.?2017. Biochem Biophys Res Commun. 483:488.
2. Shapiro F. 2016. Adv. Anat. Embryol. Cell. Biol. 221:67.
3. Saunders LR,?et al.?2015. Sci Transl Med. 7:302.
4.?Dvoriantchikova G,?et al.?2015. PLoS One. 10:e0131054.?
- Gene ID
- 13389 View all products for this Gene ID
- UniProt
- View information about DLL3 on UniProt.org