PE anti-mouse CD4 Antibody
- 产品名称:
- PE anti-mouse CD4 Antibody
- 产品类别:
- 抗体
- 产品编号:
- 116005
- 产品应用:
- 116005
- Verified Reactivity
- Mouse
- Antibody Type
- Monoclonal
- Host Species
- Rat
- Immunogen
- BALB/c mouse thymocytes
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
- Preparation
- The antibody was purified by affinity chromatography, and conjugated with PE under optimal conditions.
- Concentration
- 0.2 mg/ml
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
- Application
-
FC - Quality tested
- Recommended Usage
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤0.25 ?g per million cells in 100 ?l volume. It is recommended that the reagent be titrated for optimal performance for each application.
- Excitation Laser
- Blue Laser (488 nm)
Green Laser (532 nm)/Yellow-Green Laser (561 nm)
- Application Notes
RM4-4 antibody does not block the binding of GK1.5 and RM4-5 antibodies to CD4 T cells. For immunohistochemistry applications, the RM4-5 (Cat. No. 100506) and GK1.5 (Cat. No. 100402) antibodies are recommended.
- Application References
(PubMed link indicates BioLegend citation) -
- Bendelac A. 1995. Curr. Opin. Immunol. 7:367.
- Norian LA and Allen PM. 2004. J. Immunol. 173:835.
- Product Citations
-
- Quispe Calla N, et al. 2016. Sci Rep. 6:37723. PubMed
- Grigsby SM, et al. 2021. Cancers (Basel). 13:. PubMed
- Gern BH, et al. 2021. Cell Host Microbe. 29(4):594-606.e6. PubMed
- Schloss MJ, et al. 2022. Nat Immunol. 23:605. PubMed
- Kim D, et al. 2021. Nanomicro Lett. 13:31. PubMed
- Song C, et al. 2019. Nat Commun. 10:3745. PubMed
- Saleh MM, et al. 2019. Cell Host Microbe. 25:756. PubMed
- Pradier L, et al. 2018. Alzheimers Res Ther. 0.497916667. PubMed
- Hsu SPC, et al. 2020. J Neurooncol. 146:417. PubMed
- Lee H, et al. 2020. Cell Metabolism. 31(4):822-836. PubMed
- Rodriguez-García A, et al. 2021. Nat Commun. 12:877. PubMed
- Vicetti Miguel R, et al. 2016. PLoS One. 11: 0162445. PubMed
- Roufaiel M, et al. 2016. Nat Immunol. 10.1038/ni.3564. PubMed
- Waide ML, et al. 2020. Cell Rep. 33:108503. PubMed
- Rao E, et al. 2021. Sci Immunol. 6:. PubMed
- Su W, et al. 2020. Cell Metabolism. 32(6):996-1011.e7. PubMed
- Bartleson JM, et al. 2020. Nat Immunol. 1384:21. PubMed
- Papafragkos I, et al. 2022. Front Immunol. 13:889075. PubMed
- Guo W, et al. 2022. J Immunother Cancer. 10:. PubMed
- Xiao P, et al. 2019. J Exp Med. 216:337. PubMed
- Frazier T, et al. 2018. Adipocyte. 0.41875. PubMed
- Galvani S, et al. 2015. Sci Signal. 8: ra79. PubMed
- Garo LP, et al. 2019. Cell Rep. 28:3353. PubMed
- Horkova V, et al. 2020. Cell Reports. 30(5):1504-1514.e7.. PubMed
- Xiao L, et al. 2021. Clin Cancer Res. 27:4338. PubMed
- Moguche AO et al. 2017. Cell host & microbe. 21(6):695-706 . PubMed
- Mandal RK, et al. 2021. Cell Reports. 35(6):109094. PubMed
- Cai Z, et al. 2020. Cell Rep. 31:107816. PubMed
- Kalafati L, et al. 2020. Cell. 183:771. PubMed
- Hou Y, et al. 2021. Sci Transl Med. 13:. PubMed
- Baldwin LA, et al. 2022. Nat Commun. 13:6539. PubMed
- Wu Y, et al. 2015. J Immunol. 195: 2612-2623. PubMed
- Arensman MD, et al. 2020. Oncoimmunology. 9:1800162. PubMed
- Shi H et al. 2018. Immunity. 49(5):899-914 . PubMed
- Fasolino M, et al. 2020. Immunity. 257:52. PubMed
- Lalor R, et al. 2019. Nutrients. 11. PubMed
- Louise V Webb et al. 2019. Immunity. 50(2):348-361 . PubMed
- Johnson JL et al. 2018. Immunity. 48(2):243-257 . PubMed
- RRID
- AB_313690 (BioLegend Cat. No. 116005) AB_313691 (BioLegend Cat. No. 116006)
- Structure
- Ig superfamily, 55 kD
- Distribution
-
Majority of thymocytes, T cell subset
- Function
- TCR co-receptor, T cell activation
- Ligand/Receptor
- MHC class II molecule
- Cell Type
- T cells, Thymocytes, Tregs
- Biology Area
- Immunology
- Molecular Family
- CD Molecules
- Antigen References
-
1. Barclay A,?et al.?1997. The Leukocyte Antigen FactsBook Academic Press.?
2. Bierer BE,?et al.?1989.?Annu. Rev. Immunol.?7:579.?
3. Janeway CA. 1992.?Annu. Rev. Immunol.?10:645.
- Gene ID
- 12504 View all products for this Gene ID
- UniProt
- View information about CD4 on UniProt.org