FITC anti-mouse CD4 Antibody
- 产品名称：
- FITC anti-mouse CD4 Antibody
- 产品类别：
- 抗体
- 产品编号：
- 116003
- 产品应用：
- 116003
- Verified Reactivity
- Mouse
- Antibody Type
- Monoclonal
- Host Species
- Rat
- Immunogen
- BALB/c mouse thymocytes
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
- Preparation
- The antibody was purified by affinity chromatography, and conjugated with FITC under optimal conditions.
- Concentration
- 0.5 mg/ml
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
- Application
-
FC - Quality tested
- Recommended Usage
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤0.25 ?g per million cells in 100 ?l volume. It is recommended that the reagent be titrated for optimal performance for each application.
- Excitation Laser
- Blue Laser (488 nm)
- Application Notes
RM4-4 antibody does not block the binding of GK1.5 and RM4-5 antibodies to CD4 T cells. For immunohistochemistry applications, the RM4-5 (Cat. No. 100506) and GK1.5 (Cat. No. 100402) antibodies are recommended.
- Application References
(PubMed link indicates BioLegend citation) -
- Bendelac A. 1995. Curr. Opin. Immunol. 7:367.
- Norian LA and Allen PM. 2004. J. Immunol. 173:835.
- Product Citations
-
- Mackel JJ, et al. 2022. Front Cell Infect Microbiol. 12:974175. PubMed
- Súarez-López L, et al. 2021. iScience. 24:103406. PubMed
- Ibrahim M, et al. 2016. J Evid Based Complementary Altern Med. 21: 171 - 176. PubMed
- Montes de Oca R, et al. 2021. Mol Cancer Ther. 20:1941. PubMed
- Lyons J, et al. 2018. Sci Signal. 11. PubMed
- Jin Q, et al. 2022. Drug Des Devel Ther. 16:3297. PubMed
- Wu G, et al. 2020. Br J Pharmacol. 177:5063. PubMed
- Woodworth JS, et al. 2017. Mucosal Immunol. 0.802083333. PubMed
- Chen Y, et al. 2022. Front Immunol. 13:835690. PubMed
- Horkova V, et al. 2020. Cell Reports. 30(5):1504-1514.e7.. PubMed
- Rosenbaum SR, et al. 2020. Cell Rep. 30:510. PubMed
- Robertson TF, et al. 2021. J Cell Biol. 220:. PubMed
- Onai N, et al. 2020. Int J Mol Sci. :22. PubMed
- Benton K, et al. 2009. Regul Pept. 158:68. PubMed
- Schubert M, et al. 2021. Cancers (Basel). 13: . PubMed
- Trindade BC, et al. 2021. Immunity. 54:2273. PubMed
- RRID
- AB_313688 (BioLegend Cat. No. 116003) AB_313689 (BioLegend Cat. No. 116004)
- Structure
- Ig superfamily, 55 kD
- Distribution
-
Majority of thymocytes, T cell subset
- Function
- TCR co-receptor, T cell activation
- Ligand/Receptor
- MHC class II molecule
- Cell Type
- T cells, Thymocytes, Tregs
- Biology Area
- Immunology
- Molecular Family
- CD Molecules
- Antigen References
-
1. Barclay A,?et al.?1997. The Leukocyte Antigen FactsBook Academic Press.?
2. Bierer BE,?et al.?1989.?Annu. Rev. Immunol.?7:579.?
3. Janeway CA. 1992.?Annu. Rev. Immunol.?10:645.
- Gene ID
- 12504 View all products for this Gene ID
- UniProt
- View information about CD4 on UniProt.org
