APC anti-mouse CD4 Antibody
- 产品名称：
- APC anti-mouse CD4 Antibody
- 产品类别：
- 抗体
- 产品编号：
- 116013
- 产品应用：
- 116013
- Verified Reactivity
- Mouse
- Antibody Type
- Monoclonal
- Host Species
- Rat
- Immunogen
- BALB/c mouse thymocytes
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
- Preparation
- The antibody was purified by affinity chromatography and conjugated with APC under optimal conditions.
- Concentration
- 0.2 mg/ml
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
- Application
-
FC - Quality tested
- Recommended Usage
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤0.25 ?g per million cells in 100 ?l volume. It is recommended that the reagent be titrated for optimal performance for each application.
- Excitation Laser
- Red Laser (633 nm)
- Application Notes
RM4-4 antibody does not block the binding of GK1.5 and RM4-5 antibodies to CD4 T cells. For immunohistochemistry applications, the RM4-5 (Cat. No. 100506) and GK1.5 (Cat. No. 100402) antibodies are recommended.
- Application References
(PubMed link indicates BioLegend citation) -
- Bendelac A. 1995. Curr. Opin. Immunol. 7:367.
- Norian LA and Allen PM. 2004. J. Immunol. 173:835.
- Product Citations
-
- Gern BH, et al. 2021. Cell Host Microbe. 29(4):594-606.e6. PubMed
- Aldon Y, et al. 2020. J Immunol. 204:903. PubMed
- Bartleson JM, et al. 2020. Nat Immunol. 1384:21. PubMed
- Demircioglu F, et al. 2020. Nat Commun. 11:1290. PubMed
- Solanki A, et al. 2018. Development. 145. PubMed
- Nika L, et al. 2019. Vaccines (Basel). 7. PubMed
- Baier FA, et al. 2021. Cell Mol Gastroenterol Hepatol. 12:745. PubMed
- Pietronigro E, et al. 2019. Sci Rep. 9:12055. PubMed
- Fran?a TT, et al. 2021. JCI Insight. 6:. PubMed
- Lu X, et al. 2019. Cell Rep. 28:472. PubMed
- SL C, et al. 2016. JCI Insight. 1: 83116. PubMed
- Roberto MP, et al. 2021. Immunity. 54(8):1807-1824.e14. PubMed
- RRID
- AB_2563024 (BioLegend Cat. No. 116013) AB_2563025 (BioLegend Cat. No. 116014)
- Structure
- Ig superfamily, 55 kD
- Distribution
-
Majority of thymocytes, T cell subset
- Function
- TCR co-receptor, T cell activation
- Ligand/Receptor
- MHC class II molecule
- Cell Type
- T cells, Thymocytes, Tregs
- Biology Area
- Immunology
- Molecular Family
- CD Molecules
- Antigen References
-
1. Barclay A,?et al.?1997. The Leukocyte Antigen FactsBook Academic Press.?
2. Bierer BE,?et al.?1989.?Annu. Rev. Immunol.?7:579.?
3. Janeway CA. 1992.?Annu. Rev. Immunol.?10:645.
- Gene ID
- 12504 View all products for this Gene ID
- UniProt
- View information about CD4 on UniProt.org
