Purified anti-human CD163 Antibody
- 产品名称：
- Purified anti-human CD163 Antibody
- 产品类别：
- 抗体
- 产品编号：
- 326502
- 产品应用：
- 326502
- Verified Reactivity
- Human
- Antibody Type
- Monoclonal
- Host Species
- Mouse
- Immunogen
- Human monocytes
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
- Preparation
- The antibody was purified by affinity chromatography.
- Concentration
- 0.5 mg/mL
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C.
- Application
-
FC - Quality tested
ICC?- Reported in the literature, not verified in house
- Recommended Usage
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 2.0 ?g per million cells in 100 ?L?volume. It is recommended that the reagent be titrated for optimal performance for each application.
- Application Notes
Clone RM3/1 binds to domain 9 of CD163. Additional reported applications (for the relevant formats) include: immunofluorescence7.
- Application References
(PubMed link indicates BioLegend citation) -
- H?gger P, et al. 1998. J. Immunol. 161:1883. (FC)
- Zwadlo G, et al. 1987. Exp. Cell Biol. 55:295. (FC)
- Buechler C, et al. 2000. J. Leukoc. Biol. 67:97. (FC)
- Puig-Kroger A, et al. 2009. Cancer Res. 69:9395. (FC) PubMed
- Madsen M, et al. 2004. J. Biol. Chem. 279:51561. (FC)
- Jones K, et al. 2013. Clin Cancer Res. 19:731. (FC) PubMed
- Stewart DA, et al. 2012. Mol. Cancer Res. 10:727. (IF)
- Product Citations
-
- Talbot H, et al. 2020. Sci Rep. 10:12572. PubMed
- Stewart D, et al. 2012. Mol Cancer Res. 0.921527778. PubMed
- Cho H, et al. 2007. Physiol Genomics. 29:149. PubMed
- RRID
- AB_893267 (BioLegend Cat. No. 326502)
- Structure
- 134 kD (non-reduced)/155 kD (reduced) glycoprotein, Scavenger receptor superfamily
- Distribution
-
Monocytes, macrophages, Kuffer cells, subset of dendritic cells, subset of hematopoietic stem/progenitor cells
- Function
- Clearance of haptoglobin-hemoglobin complex, regulation of cytokine production by macrophages
- Ligand/Receptor
- Haptoglobin-hemoglobin complex, TWEAK
- Cell Type
- Dendritic cells, Hematopoietic stem and progenitors, Macrophages, Monocytes
- Biology Area
- Cell Biology, Immunology, Neuroscience, Neuroscience Cell Markers
- Molecular Family
- CD Molecules
- Antigen References
-
1. Roth J, et al. 1994. Transolantation. 57:127.
2. Van den Heuvel MM, et al.1999. J. Leukoc. Biol. 66:858.
3. Sulahian TH, et al. 2000. Cytokines 12:1312.
4. Fabriek BO, et al. 2007. J. Neuroimmunol. 187:179.
- Gene ID
- 9332 View all products for this Gene ID
- UniProt
- View information about CD163 on UniProt.org
