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首页 > 抗体蛋白 > 抗体
Purified anti-O-GlcNAc Antibody
产品名称：
Purified anti-O-GlcNAc Antibody
产品类别：
抗体
产品编号：
677902
产品应用：
677902
[价格]
规格 价格 库存
100µg ￥ 4858 1

产品详情

Product Details

Verified Reactivity
Beta-O-linked N-acetylglucosamine (O-GlcNAc) in all metazoans including plants, animals, and the viruses that infect them
Antibody Type
Monoclonal
Host Species
Mouse
Immunogen
O-GlcNAc in beta-O-glycosidic linkage to both serine and threonine.
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation
The antibody was purified by affinity chromatography.
Concentration
0.5 mg/mL
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C.
Application

WB - Quality tested
ICC, IHC, IP - Reported in the literature, not verified in house
Recommended Usage

Each lot of this antibody is quality control tested by Western blotting. For Western blotting, the suggested use of this reagent is 0.5 - 2.5 ?g per mL. It is recommended that the reagent be titrated for optimal performance for each application.

Application References

(PubMed link indicates BioLegend citation)
  1. Snow CM, et al. 1987. J. Cell Biol. 104:1143.
  2. Shin SH, et al. 2011. Amino Acids 40:885-93.
  3. Mi W, et al. 2011. Biochim. Biophys. Acta. 4:514.
  4. Hoedt E, et al. 2010. J. Biol. Chem. 285:19205.
Product Citations
  1. Wang Z, et al. 2020. Theranostics. 5.401388889. PubMed
  2. Li R, et al. 2021. Shock. 56:755. PubMed
RRID
AB_2565912 (BioLegend Cat. No. 677902)

Antigen Details

Structure
O-GlcNAc modified protein.
Distribution

Nucleus and cytoplasm.

Function
To prevent O-phosphorylation and to modulate signaling and transcription in response to cellular nutrients or stress.
Biology Area
Cell Biology, Signal Transduction, Transcription Factors
Molecular Family
Protein Kinases/Phosphatase
Antigen References

1. Comer FI, et al. 2001. Anal Biochem. 293:169.
2. Hart, GW and Akimoto, Y. (2009) Essentials of Glycobiology, 2nd edition. Cold Spring Harbor, NY: Cold Spring Harbor Laboratory Press.
3. de Queiroz RM, et al. 2014. Front Oncol. 4:132.
4. Hart GW, et al. 2014. Cell Metab. 20:208.

Gene ID
8473 View all products for this Gene ID
UniProt
View information about O-GlcNAc on UniProt.org

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