PE anti-mouse CD55 (DAF) Antibody
- 产品名称：
- PE anti-mouse CD55 (DAF) Antibody
- 产品类别：
- 抗体
- 产品编号：
- 131803
- 产品应用：
- 131803
- Verified Reactivity
- Mouse
- Antibody Type
- Monoclonal
- Host Species
- Armenian Hamster
- Immunogen
- Transfected cells
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
- Preparation
- The antibody was purified by affinity chromatography, and conjugated with PE under optimal conditions.
- Concentration
- 0.2 mg/ml
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
- Application
-
FC - Quality tested
- Recommended Usage
- Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤0.25 ?g per million cells in 100 ?l volume. It is recommended that the reagent be titrated for optimal performance for each application.
- Excitation Laser
- Blue Laser (488 nm)
Green Laser (532 nm)/Yellow-Green Laser (561 nm)
- Application References
(PubMed link indicates BioLegend citation) -
- Cao Q, et al. 2012. Am J Physiol Cell Physiol. 302:1731. PubMed.
- Product Citations
-
- Camps J, et al. 2020. Cell Reports. 31(5):107597. PubMed
- Scott CL et al. 2018. Immunity. 49(2):312-325 . PubMed
- Di Genua C, et al. 2020. Cancer Cell. 37(5):690-704.e8.. PubMed
- Pal B, et al. 2017. Nat Commun.. 10.1038/s41467-017-01560-x. PubMed
- Yan Q, et al. 2017. PLoS One. 12(6):e0179033. PubMed
- Thomson CA, et al. 2018. J Immunol. 201:215. PubMed
- RRID
- AB_1279267 (BioLegend Cat. No. 131803) AB_1279265 (BioLegend Cat. No. 131804)
- Structure
- 60-70 kd single chain glycoprotein. While human CD55 contains only one CD55 gene, two distinct CD55 genes have been identified in the mouse, referred to as GPI-DAF and transmembrane(TM)-DAF. GPI-DAF is expressed only in testis.
- Distribution
-
Red blood cells and most of the splenocytes, including B cells and T cells, and also many non-hematopoetic cells.
- Function
- Protect from complement attack by inhibition the deposition of C3 on antibody-sensitized cells.
- Cell Type
- B cells, Erythrocytes, T cells
- Biology Area
- Cell Biology, Costimulatory Molecules, Immunology, Neuroinflammation, Neuroscience
- Molecular Family
- CD Molecules
- Antigen References
-
1. Miwa T et al. 2001. Immunology 104:207
2. Lin FY et al. 2001 Immunology 104:215
- Gene ID
- 13136 View all products for this Gene ID
- UniProt
- View information about CD55 on UniProt.org
