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PE anti-mouse CD71 Antibody
产品名称:
PE anti-mouse CD71 Antibody
产品类别:
抗体
产品编号:
113807
产品应用:
113807
[价格]
规格 价格 库存
50µg ¥ 1302 1

产品详情

Product Details

Verified Reactivity
Mouse
Antibody Type
Monoclonal
Host Species
Rat
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation
The antibody was purified by affinity chromatography, and conjugated with PE under optimal conditions.
Concentration
0.2 mg/ml
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
Application

FC - Quality tested

Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 0.25 ?g per 106 cells in 100 ?l volume. It is recommended that the reagent be titrated for optimal performance for each application.

Excitation Laser
Blue Laser (488 nm)
Green Laser (532 nm)/Yellow-Green Laser (561 nm)
Application Notes

Additional reported applications (for the relevant formats) include: blocking of cellular proliferation. The Ultra-LEAF? purified antibody (Endotoxin < 0.01 EU/?g, Azide-Free, 0.2 ?m filtered) is recommended for functional assays (Cat. Nos. 113821 & 113822).

This clone may also be known as R17217 or R17 217.

Application References

(PubMed link indicates BioLegend citation)
  1. Trowbridge I, et al. 1982. J. Cell. Physiol. 112:403.
  2. Grisendi S, et al. 2005. Nature 437:147.
  3. van Rooy I, et al. 2010. J. Control Release 150:30. PubMed
  4. Willhelm BT, et al. 2011. Blood 117:27. PubMed
  5. Okasi Y, et al. 2012. Exp Hematol. 40:143PubMed
  6. Stojanov K, et al. 2012. Mol Pharm. 9:1620. PubMed
Product Citations
  1. Han X, et al. 2017. Int J Mol Sci. 10.3390/ijms18050942. PubMed
  2. Viny AD, et al. 2019. Cell Stem Cell. 25:682. PubMed
  3. Yeo GHT, et al. 2020. Cell Stem Cell. 26(6):938-950.e6. PubMed
  4. Lutzmann M, et al. 2019. Cell Rep. 28:2851. PubMed
  5. Liu P, et al. 2020. Genome Res. 30:1655. PubMed
  6. Liu J, et al. 2012. PLoS One. 7:e44044. PubMed
  7. Dey A et al. 2019. The EMBO journal. 38(7) pii: e100293. PubMed
  8. Greenblatt SM, et al. 2018. Cancer Cell. 33:1111. PubMed
  9. Huang P, et al. 2020. Blood. 135:2121. PubMed
  10. Kunimoto H, et al. 2018. Cancer Cell. 33:44. PubMed
  11. Uchil PD et al. 2018. Cell host & microbe. 25(1):87-100 . PubMed
  12. Di Genua C, et al. 2020. Cancer Cell. 37(5):690-704.e8.. PubMed
  13. Frost JN, et al. 2021. Med (N Y). 2:164. PubMed
  14. Mehta C, et al. 2021. Nucleic Acids Res. 49:9007. PubMed
  15. Tojo Y, et al. 2015. Mol Cell Biol. 35: 2658-2672. PubMed
  16. Lu Y, et al. 2020. Immunity. 52:782. PubMed
  17. Hou Y, et al. 2021. Sci Transl Med. 13:. PubMed
  18. Lehrke MJ, et al. 2021. Elife. 10:. PubMed
  19. Shi H, et al. 2020. Immunity. 51(6):1012-1027.e7.. PubMed
  20. Yokomizo-Nakano T, et al. 2020. Cancer Res. 80:2523. PubMed
  21. Chen C, et al. 2020. Cell Rep. 2136:30. PubMed
  22. Heil J, et al. 2021. Nat Commun. 12:6963. PubMed
  23. Xu C, et al. 2021. Cell Reports. 35(11):109235. PubMed
  24. Yin Y, et al. 2016. J Biol Chem. 291: 6923 - 6935. PubMed
  25. Peltzer N, et al. 2018. Nature. 557:112. PubMed
  26. Timilshina M, et al. 2020. Cell Reports. 27(10):2948-2961.e7.. PubMed
  27. Long L, et al. 2021. Nature. 600:308. PubMed
  28. Awida Z, et al. 2021. Int J Mol Sci. 23:. PubMed
  29. Li Z, et al. 2021. J Mol Histol. . PubMed
RRID
AB_313568 (BioLegend Cat. No. 113807) AB_313569 (BioLegend Cat. No. 113808)

Antigen Details

Structure
Transferrin receptor and is 95 kD.
Distribution

Most dividing cells, the brain endothelium, and cycling hematopoietic progenitors.

Function
Mediates iron uptake.
Ligand/Receptor
Transferrin.
Cell Type
Hematopoietic stem and progenitors
Biology Area
Immunology
Molecular Family
CD Molecules
Antigen References

1. Hentze MW, et al. 1996. P. Natl. Acad. Sci. USA 93:8175.
2. Trowbridge IS, et al. 1993. Annu. Rev. Cell Biol. 9:129.
3. Trowbridge I, et al. 1982. J. Cell Physiol. 112:403.
4. Kuhn LC, et al. 1984. Cell 37:95.

Gene ID
22042 View all products for this Gene ID
UniProt
View information about CD71 on UniProt.org

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