APC anti-mouse CD71 Antibody
- 产品名称:
- APC anti-mouse CD71 Antibody
- 产品类别:
- 抗体
- 产品编号:
- 113819
- 产品应用:
- 113819
- Verified Reactivity
- Mouse
- Antibody Type
- Monoclonal
- Host Species
- Rat
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
- Preparation
- The antibody was purified by affinity chromatography and conjugated with APC under optimal conditions.
- Concentration
- 0.2 mg/ml
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
- Application
-
FC - Quality tested
- Recommended Usage
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤0.125 ?g per million cells in 100 ?l volume. It is recommended that the reagent be titrated for optimal performance for each application.
- Excitation Laser
- Red Laser (633 nm)
- Application Notes
Additional reported applications (for the relevant formats) include: blocking of cellular proliferation. The Ultra-LEAF? purified antibody (Endotoxin < 0.01 EU/?g, Azide-Free, 0.2 ?m filtered) is recommended for functional assays (Cat. Nos. 113821 & 113822).
This clone may also be known as R17217 or R17 217.
- Application References
(PubMed link indicates BioLegend citation) -
- Trowbridge I, et al. 1982. J. Cell. Physiol. 112:403.
- Grisendi S, et al. 2005. Nature 437:147.
- van Rooy I, et al. 2010. J. Control Release 150:30. PubMed
- Willhelm BT, et al. 2011. Blood 117:27. PubMed
- Okasi Y, et al. 2012. Exp Hematol. 40:143PubMed
- Stojanov K, et al. 2012. Mol Pharm. 9:1620. PubMed
- Product Citations
-
- Hodzic D, et al. 2022. PLoS Biol. 20:e3001811. PubMed
- Kotaki R, et al. 2020. Sci Rep. 10:13554. PubMed
- De Santi C, et al. 2022. Mol Ther Nucleic Acids. 29:643. PubMed
- Reinfeld BI, et al. 2021. Nature. 593:282. PubMed
- Jeziorska DM, et al. 2022. Nat Commun. 13:6641. PubMed
- Daneshmandi S, et al. 2021. Elife. 10:. PubMed
- Yoshinaga M, et al. 2022. Nat Commun. 13:6435. PubMed
- Kim DJ, et al. 2020. Proc Natl Acad Sci U S A. 117:15837. PubMed
- RRID
- AB_2728134 (BioLegend Cat. No. 113819) AB_2728135 (BioLegend Cat. No. 113820)
- Structure
- Transferrin receptor and is 95 kD.
- Distribution
-
Most dividing cells, the brain endothelium, and cycling hematopoietic progenitors.
- Function
- Mediates iron uptake.
- Ligand/Receptor
- Transferrin.
- Cell Type
- Hematopoietic stem and progenitors
- Biology Area
- Immunology
- Molecular Family
- CD Molecules
- Antigen References
-
1. Hentze MW, et al. 1996. P. Natl. Acad. Sci. USA 93:8175.
2. Trowbridge IS, et al. 1993. Annu. Rev. Cell Biol. 9:129.
3. Trowbridge I, et al. 1982. J. Cell Physiol. 112:403.
4. Kuhn LC, et al. 1984. Cell 37:95.
- Gene ID
- 22042 View all products for this Gene ID
- UniProt
- View information about CD71 on UniProt.org