Purified anti-mouse CD201 (EPCR) Antibody
- 产品名称:
- Purified anti-mouse CD201 (EPCR) Antibody
- 产品类别:
- 抗体
- 产品编号:
- 141501
- 产品应用:
- 141501
- Verified Reactivity
- Mouse
- Antibody Type
- Monoclonal
- Host Species
- Rat
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
- Preparation
- The antibody was purified by affinity chromatography.
- Concentration
- 0.5 mg/ml
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C.
- Application
-
FC - Quality tested
- Recommended Usage
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤1.0 ?g per million cells in 100 ?l volume. It is recommended that the reagent be titrated for optimal performance for each application.
- Application Notes
Additional reported applications (for the relevant formats) include: in vivo and in vitro blocking of protein C binding1.
- Application References
(PubMed link indicates BioLegend citation) -
- Centelles MN, et al. 2010. Thromb Haemost. 103:1239. (Block)
- Product Citations
-
- Tanaka Y, et al. 2015. PLoS One. 10: 0138621. PubMed
- RRID
- AB_10899573 (BioLegend Cat. No. 141501)
- Structure
- Type I transmembrane glycoprotein, 46 kD
- Distribution
-
Endothelial cells, subset of hematopoietic stem cells, subset of dendritic cells
- Function
- Inhibits blood coagulation, apoptosis, inflammation, endothelial activation
- Interaction
- Protease-activated receptor 1 (Par-1)
- Ligand/Receptor
- Protein C, activated protein C
- Cell Type
- Dendritic cells, Endothelial cells, Hematopoietic stem and progenitors
- Biology Area
- Apoptosis/Tumor Suppressors/Cell Death, Cell Biology, Costimulatory Molecules, Immunology
- Molecular Family
- CD Molecules
- Antigen References
-
1. Kerschen E, et al. 2010. J. Clin. Invest. 120:3167.
2. Iwasaki H, et al. 2010. Blood 116:544.
3. Balazs AB, et al. 2006. Blood 107:2317.
- Gene ID
- 19124 View all products for this Gene ID
- UniProt
- View information about CD201 on UniProt.org