APC anti-mouse CD201 (EPCR) Antibody
- 产品名称：
- APC anti-mouse CD201 (EPCR) Antibody
- 产品类别：
- 抗体
- 产品编号：
- 141505
- 产品应用：
- 141505
- Verified Reactivity
- Mouse
- Antibody Type
- Monoclonal
- Host Species
- Rat
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
- Preparation
- The antibody was purified by affinity chromatography and conjugated with APC under optimal conditions.
- Concentration
- 0.2 mg/ml
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
- Application
-
FC - Quality tested
- Recommended Usage
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤0.5 ?g per million cells in 100 ?l volume. It is recommended that the reagent be titrated for optimal performance for each application.
- Excitation Laser
- Red Laser (633 nm)
- Application Notes
Additional reported applications (for the relevant formats) include: in vivo and in vitro blocking of protein C binding1.
- Application References
(PubMed link indicates BioLegend citation) -
- Centelles MN, et al. 2010. Thromb Haemost. 103:1239. (Block)
- Product Citations
-
- Fukushima T, et al. 2019. Cell Rep. 29:4144. PubMed
- Mantri CK, et al. 2019. J Clin Invest. 129:1094. PubMed
- Chen X et al. 2017. Cell stem cell. 21(6):747-760 . PubMed
- Elahi S, et al. 2020. Stem Cell Res. 43:101710. PubMed
- Cai S et al. 2017. Cell stem cell. 20(2):247-260 . PubMed
- Chen R, et al. 2021. Cell Reports. 34(7):108751. PubMed
- RRID
- AB_2561361 (BioLegend Cat. No. 141505) AB_2561362 (BioLegend Cat. No. 141506)
- Structure
- Type I transmembrane glycoprotein, 46 kD
- Distribution
-
Endothelial cells, subset of hematopoietic stem cells, subset of dendritic cells
- Function
- Inhibits blood coagulation, apoptosis, inflammation, endothelial activation
- Interaction
- Protease-activated receptor 1 (Par-1)
- Ligand/Receptor
- Protein C, activated protein C
- Cell Type
- Dendritic cells, Endothelial cells, Hematopoietic stem and progenitors
- Biology Area
- Apoptosis/Tumor Suppressors/Cell Death, Cell Biology, Costimulatory Molecules, Immunology
- Molecular Family
- CD Molecules
- Antigen References
-
1. Kerschen E, et al. 2010. J. Clin. Invest. 120:3167.
2. Iwasaki H, et al. 2010. Blood 116:544.
3. Balazs AB, et al. 2006. Blood 107:2317.
- Gene ID
- 19124 View all products for this Gene ID
- UniProt
- View information about CD201 on UniProt.org
