PE anti-mouse CD265 (RANK) Antibody
- 产品名称：
- PE anti-mouse CD265 (RANK) Antibody
- 产品类别：
- 抗体
- 产品编号：
- 119805
- 产品应用：
- 119805
- Verified Reactivity
- Mouse
- Antibody Type
- Monoclonal
- Host Species
- Rat
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
- Preparation
- The antibody was purified by affinity chromatography, and conjugated with PE under optimal conditions.
- Concentration
- 0.2 mg/ml
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
- Application
-
FC - Quality tested
- Recommended Usage
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤1.0 ?g per 106 cells in 100 ?l volume. It is recommended that the reagent be titrated for optimal performance in each application.
- Excitation Laser
- Blue Laser (488 nm)
Green Laser (532 nm)/Yellow-Green Laser (561 nm)
- Application References
(PubMed link indicates BioLegend citation) -
- Hildebrand D, et al. 2010. Infect. Immun. 79:220. PubMed
- Product Citations
-
- Hildebrand D, et al. 2010. Infect Immun. 79:220. PubMed
- Holoshitz J, et al. 2013. J Immunol. 190:48. PubMed
- Ha J, et al. 2010. J Immunol. 184:4717. PubMed
- Santhanam L, et al. 2021. J Clin Invest. 131:. PubMed
- Xia W, et al. 2013. J Cell Biol. 200:821. PubMed
- Adamopoulos I, et al. 2015. Ann Rheum Dis. 74:1284. PubMed
- RRID
- AB_2205354 (BioLegend Cat. No. 119805) AB_2205353 (BioLegend Cat. No. 119806)
- Structure
- TNF superfamily member, Type I membrane protein
- Distribution
- Ubiquitous expression; highest levels in trabecular bone, thymus, small intestine, lung, brain, and kidney. Weakly expressed in spleen and bone marrow.
- Function
- Essential for RANK ligand mediated osteoclastogenesis. Involved in the interactions between T cells and dendritic cells
- Interaction
- Cytoplasmic domain interacts with TRAF2, TRAF5, and TRAF6
- Ligand/Receptor
- Receptor for RANK ligand/TRANCE/OPGL
- Biology Area
- Cell Biology, Immunology
- Molecular Family
- CD Molecules
- Antigen References
-
1. Anderson DM, et al. 1997. Nature 390:175.
2. Nakagawa N, et al. 1998. Biochem. Biophys. Res. Commun. 253:395.
3. Ha J, et al. 2010. J. Immunol. 184:4717.
- Gene ID
- 21934 View all products for this Gene ID
- UniProt
- View information about CD265 on UniProt.org
