APC anti-mouse CD265 (RANK) Antibody
- 产品名称：
- APC anti-mouse CD265 (RANK) Antibody
- 产品类别：
- 抗体
- 产品编号：
- 119807
- 产品应用：
- 119807
- Verified Reactivity
- Mouse
- Antibody Type
- Monoclonal
- Host Species
- Rat
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide
- Preparation
- The antibody was purified by affinity chromatography and conjugated with APC under optimal conditions.
- Concentration
- 0.2 mg/mL
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
- Application
-
FC - Quality tested
- Recommended Usage
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 1.0 ?g per million cells in 100 ?L volume. It is recommended that the reagent be titrated for optimal performance for each application.
- Excitation Laser
- Red Laser (633 nm)
- Application References
(PubMed link indicates BioLegend citation) -
- Hildebrand D, et al. 2010. Infect. Immun. 79:220. PubMed
- RRID
- AB_2892276 (BioLegend Cat. No. 119807) AB_2892276 (BioLegend Cat. No. 119808)
- Structure
- TNF superfamily member, Type I membrane protein
- Distribution
-
Ubiquitous expression; highest levels in trabecular bone, thymus, small intestine, lung, brain, and kidney. Weakly expressed in spleen and bone marrow.
- Function
- Essential for RANK ligand mediated osteoclastogenesis. Involved in the interactions between T cells and dendritic cells
- Interaction
- Cytoplasmic domain interacts with TRAF2, TRAF5, and TRAF6
- Ligand/Receptor
- Receptor for RANK ligand/TRANCE/OPGL
- Biology Area
- Cell Biology, Immunology
- Molecular Family
- CD Molecules
- Antigen References
-
- Anderson DM, et al. 1997. Nature. 390:175.
- Nakagawa N, et al. 1998. Biochem?Biophys?Res?Commun. 253:395.
- Ha J, et al. 2010. J?Immunol. 184:4717.
- Gene ID
- 21934 View all products for this Gene ID
- UniProt
- View information about CD265 on UniProt.org
