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Purified anti-human CD111 (Nectin-1) Antibody
产品名称:
Purified anti-human CD111 (Nectin-1) Antibody
产品类别:
抗体
产品编号:
340402
产品应用:
340402
[价格]
规格 价格 库存
100µg ¥ 4522 1

产品详情

Product Details

Verified Reactivity
Human
Antibody Type
Monoclonal
Host Species
Mouse
Immunogen
Human Nectin-1 transfected NIH/3T3 cells
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation
The antibody was purified by affinity chromatography.
Concentration
0.5 mg/ml
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C.
Application

FC - Quality tested
IHC-P - Verified
WB, IP - Reported in the literature, not verified in house

Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤1.0 ?g per million cells in 100 ?l volume. For immunohistochemical staining on formalin-fixed paraffin-embedded tissue sections, the suggested use of this reagent is 5.0 - 10.0 ?g per ml. It is recommended that the reagent be titrated for optimal performance for each application.

Application Notes

Additional reported applications (for relevant formats) include: immunoprecipitation, Western blot, immunohistochemical staining of frozen tissue sections, block HSV-1 and HSV-2 entry into cells.

Application References

(PubMed link indicates BioLegend citation)
  1. Cocchi F, et al. 1998. Proc. Natl. Acad. Sci. USA. 95:15700.
  2. Martinez WM and Spear PG. 2002. J. Virol. 76:7255.
  3. Reymond N,et al. 2004. J. Exp Med. 199:1331.
RRID
AB_2284683 (BioLegend Cat. No. 340402)

Antigen Details

Structure
75 kD type I transmembrane glycoprotein, Nectin family, Ig superfamily
Distribution

Myelomonocytic cells, megakaryocytes, CD34-positive stem cells, endothelial cells, epithelial cells, and neuronal cells.

Function
Adhesion, receptor for Herpes simplex Virus 1 (HSV-1) and HSV-2
Ligand/Receptor
Nectin-1, -2, -3, and -4, CD155, HSV-1 and HSV-2
Cell Type
Endothelial cells, Epithelial cells, Hematopoietic stem and progenitors, Megakaryocytes
Biology Area
Cell Biology, Immunology, Neuroscience, Synaptic Biology
Molecular Family
Adhesion Molecules, CD Molecules
Antigen References

1. Zola h, et al. 2007. Leukocyte and Stromal Cell Molecules:The CD Markers. Wiely-Liss A John Wiley & Sons Inc, Publication.
2. Simpson SA, et al. 2005. J. Neuroviral. 11:208.
3. Akhtar J, et al. 2008. Ophthalmol. Vis. Sci. 49:4026.

Gene ID
5818 View all products for this Gene ID
UniProt
View information about CD111 on UniProt.org

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