Alexa Fluor® 594 anti-human MRP1 (ABCC1) Antib-上海雅吉生物科技有限公司

规格	价格	库存
100µg	￥ 4858	1

Product Details

Verified Reactivity: Human
Antibody Type: Monoclonal
Host Species: Mouse
Immunogen: QCRL-1 was raised against membranes prepared from the human small cell lung cancer cell line, H69AR, which highly over expresses MRP1.
Formulation: Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation: The antibody was purified by affinity chromatography and conjugated with Alexa Fluor? 594 under optimal conditions.
Concentration: 0.5 mg/ml
Storage & Handling: The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
Application: IHC-P - Quality tested
Recommended Usage: Each lot of this antibody is quality control tested by formalin-fixed paraffin-embedded immunohistochemical staining. For immunohistochemistry, a concentration range of 1.25 - 5.0 ?g/ml is suggested. It is recommended that the reagent be titrated for optimal performance for each application.

* Alexa Fluor? 594 has an excitation maximum of 590 nm, and a maximum emission of 617 nm.

Alexa Fluor? and Pacific Blue? are trademarks of Life Technologies Corporation.

View full statement regarding label licenses
Application Notes: QCRL-1 detects a linear epitope and has been mapped to aa 918-924. It has been reported that QCRL-1 does not inhibit MRP1 transport activity. QCRL-1, QCRL-2, QCRL-3, and QCRL-4 each bind distinct non-overlapping epitopes.
RRID: AB_2632715 (BioLegend Cat. No. 370106)

Antigen Details

Structure: 190 kD integral membrane phosphoglycoprotein.
Distribution: Testes, lung, skin, small intestine, colon, kidney, placenta, peripheral blood mononuclear cells, and skeletal muscle. Cytoplasm / plasma membrane.
Function: Extrusion of drugs from the cell.
Biology Area: Immunology
Antigen References: 1. Cole SP, et al. 2014. Annu. Rev. Pharmacol. Toxicol. 54:95.
2. Hipfner DR, et al. 1999. J. Biol. Chem. 274(22):15420.
3. Filipits M, et al. 1999. Anticancer Res. 6:5043.
4. Wright SR, et al. 1998. Clin. Cancer Res. 4:2279.
5. Hipfner DR, et al. 1998. Br. J. Cancer 78(9):1134.
6. Filipits M, et al. 1997. Leukemia 11(7):1073.
7. Loe DW, et al. 1997. Mol. Pharmacol. 6:1034-41.
8. Hipfner DR, et al. 1996. Cancer Res. 56:3307.
9. Filipits M, et al. 1996. Clin. Cancer Res. 2(7):1231.
10. Almquist KC, et al. 1995. Cancer Res. 55(1):102.
Gene ID: 4363 View all products for this Gene ID
UniProt: View information about MRP1 on UniProt.org

上海细胞库

原代细胞

细胞培养

细胞服务

酶联试剂盒

生化试剂盒

PCR试剂盒

抗体蛋白

试剂耗材

首页 > 抗体蛋白 > 抗体

产品详情

Product Details

Antigen Details

联系我们