Purified anti-mouse KLRG1 (MAFA) Recombinant Antib
- 产品名称：
- Purified anti-mouse KLRG1 (MAFA) Recombinant Antib
- 产品类别：
- 抗体
- 产品编号：
- 164902
- 产品应用：
- 164902
- Verified Reactivity
- Mouse
- Antibody Type
- Recombinant
- Host Species
- Rat
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide
- Preparation
- The antibody was purified by affinity chromatography.
- Concentration
- 0.5 mg/mL
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C.
- Application
-
FC - Quality tested
- Recommended Usage
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 0.25 ?g per million cells in 100 ?L volume. It is recommended that the reagent be titrated for optimal performance for each application.
- Application Notes
Clone QA20A64 completely block the binding of reported clone 2F1/KLRG1 on target cells.
- RRID
- AB_2910348 (BioLegend Cat. No. 164902)
- Structure
- KLRG1 is an inhibitory lectin-like type II transmembrane receptor containing a cytoplasmic motif similar to ITIM, expressed mainly as a homodimeric molecule consisting of two N-glycosylated subunits of approximately 30-38 kD.
- Distribution
-
Subsets of NK cells, lymphokine-activated killer (LAK) cells and subsets of CD8+ and CD4+ cells.
- Function
- Regulates NK cell proliferation, maturation, and homeostasis. Inhibits immune responses by regulating the effector function and the developmental processes of NK and T cells.
- Interaction
- NK cells, T cells, Tregs
- Ligand/Receptor
- E-cadherin
- Cell Type
- NK cells, T cells
- Biology Area
- Immunology, Innate Immunity
- Antigen References
-
- Grundemann C, et al. 2006. J. Immunol. 176:1311-5.
- Blaser C, et al. 1998. J. Immunol. 161:6451-4.
- Huntington ND, et al. 2007. J. Immunol. 178:4764-70.
- Voehringer D, et al. 2001. J. Immunol. 167:4838-43.
- Gene ID
- 10219 View all products for this Gene ID
- UniProt
- View information about KLRG1 on UniProt.org
