Purified anti-mouse CD326 (Ep-CAM) Recombinant Ant
- 产品名称:
- Purified anti-mouse CD326 (Ep-CAM) Recombinant Ant
- 产品类别:
- 抗体
- 产品编号:
- 119002
- 产品应用:
- 119002
- Verified Reactivity
- Mouse
- Antibody Type
- Recombinant
- Host Species
- Rat
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide
- Preparation
- The antibody was purified by affinity chromatography.
- Concentration
- 0.5 mg/mL
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C.
- Application
-
FC - Quality tested
- Recommended Usage
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 0.25 ?g per million cells in 100 ?L volume. It is recommended that the reagent be titrated for optimal performance for each application.
- Application Notes
Clone QA20B19 can completely block the binding of parental clone to target cells.
- Structure
- 40 kD single-pass type 1 glycoprotein. 293 amino acids, with a 21 aa signal peptide, a 246 aa extracellular domain, a 21 aa transmembrane domain, and a 26 aa cytoplasmic domain. The extracellular domain contains two epidermal growth factor-like repeats.
- Distribution
-
Expressed on majority of epithelial cell membranes with the exception of adult squamous cells of the skin and a few specific epithelial cell types
- Function
- Mediates calcium-independent homophilic cell-cell adhesion
- Interaction
- CD326 displays hemophilic binding
- Ligand/Receptor
- CD305 (LAIR-1), CD306 (LAIR-2), and Ep-CAM
- Antigen References
-
- Borkowski TA, et al. 1996. Eur J?Immunol. 26:110-4.
- Bergsagel PL, et al. 1992. J?Immunol.?148:590-6.
- Gene ID
- 17075 View all products for this Gene ID
- UniProt
- View information about CD326 on UniProt.org