Purified anti-human T-bet Recombinant Antibody
- 产品名称：
- Purified anti-human T-bet Recombinant Antibody
- 产品类别：
- 抗体
- 产品编号：
- 365902
- 产品应用：
- 365902
- Verified Reactivity
- Human
- Antibody Type
- Recombinant
- Host Species
- Mouse
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide
- Preparation
- The antibody was purified by affinity chromatography.
- Concentration
- 0.5 mg/mL
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C.
- Application
-
ICFC - Quality tested
- Recommended Usage
Each lot of this antibody is quality control tested by intracellular immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 0.125 ?g per million cells in 100 ?L volume. It is recommended that the reagent be titrated for optimal performance for each application.
- Application Notes
Clone QA18A24 can completely block the binding of clone 4B10 on target cells.
- RRID
- AB_2904398 (BioLegend Cat. No. 365902)
- Structure
- T-box transcription factor, approximately 58 kD.
- Distribution
-
Nuclear; expressed in T cells, hematopoietic stem cells, NK cells, B cells, lung, spleen.
- Function
- Th1-specific T-box transcription factor controlling expression of the hallmark Th1 cytokine, interferon gamma (IFN-γ). T-bet expression is critical for the control of microbial pathogens.
- Interaction
- Human
- Cell Type
- B cells, Hematopoietic stem and progenitors, NK cells, T cells, Tregs
- Biology Area
- Cell Biology, Immunology, Transcription Factors
- Molecular Family
- Nuclear Markers
- Antigen References
-
- Szabo SJ, et al. 2000. Cell. 100:655-69.
- Szabo SJ, et al. 2002. Science. 295:338-42.
- Finotto S, et al. 2002. Science. 295:336-8.
- Mullen AC, et al. 2001. Science.?292:1907-10.
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- Gene ID
- 30009 View all products for this Gene ID
- UniProt
- View information about T-bet on UniProt.org
