PE anti-human T-bet Recombinant Antibody -上海雅吉生物科技有限公司

规格	价格	库存
25tests	￥ 2310	1

Product Details

Verified Reactivity: Human
Antibody Type: Recombinant
Host Species: Mouse
Formulation: Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
Preparation: The antibody was purified by affinity chromatography and conjugated with PE under optimal conditions.
Concentration: Lot-specific (to obtain lot-specific concentration, please enter the lot number in our Concentration and Expiration Lookup or Certificate of Analysis online tools.)
Storage & Handling: The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
Application: ICFC - Quality tested
Recommended Usage: Each lot of this antibody is quality control tested by intracellular immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 ?L per million cells in 100 ?L staining volume or 5 ?L per 100 ?L of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.
Excitation Laser: Blue Laser (488 nm)
Green Laser (532 nm)/Yellow-Green Laser (561 nm)
Application Notes: Clone QA18A24 can completely block the binding of clone 4B10 on target cells.
RRID: AB_2922579 (BioLegend Cat. No. 365903) AB_2922579 (BioLegend Cat. No. 365904)

Antigen Details

Structure

T-box transcription factor, approximately 58 kD.

Distribution

Nuclear; expressed in T cells, hematopoietic stem cells, NK cells, B cells, lung, spleen.

Function

Th1-specific T-box transcription factor controlling expression of the hallmark Th1 cytokine, interferon gamma (IFN-γ). T-bet expression is critical for the control of microbial pathogens.

Interaction

Human

Cell Type

B cells, Hematopoietic stem and progenitors, NK cells, T cells, Tregs

Biology Area

Cell Biology, Immunology, Transcription Factors

Molecular Family

Nuclear Markers

Antigen References