Purified anti-mouse CD45 Recombinant Antibody -上海雅吉生物科技有限公司

规格	价格	库存
500µg	￥ 3052	1

Product Details

Verified Reactivity

Mouse

Antibody Type

Recombinant

Host Species

Mouse

Immunogen

Mouse thymus or spleen

Formulation

Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.

Preparation

The antibody was purified by affinity chromatography.

Concentration

0.5 mg/ml

Storage & Handling

The antibody solution should be stored undiluted between 2°C and 8°C.

Application

FC - Quality tested
IHC-F, IHC-P, WB, IP - Reported in the literature, not verified in house

Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 0.125 ?g per million cells in 100 ?l volume. It is recommended that the reagent be titrated for optimal performance for each application.

Application Notes

The QA17A26 antibody can block 30-F11 clone? and vice versa. The clone QA17A26 reacts with all isoforms and both CD45.1 and CD45.2 alloantigens of CD45.

Application References (PubMed link indicates BioLegend citation)

Podd BS, et al. 2006. J. Immunol. 176:6532. (FC, CMCD) PubMed
Haynes NM, et al. 2007. J. Immunol. 179:5099. (FC)
Ledbetter JA, et al. 1979. Immunol. Rev. 47:63. (IP)
Simon DI, et al. 2000. J. Clin. Invest. 105:293. (IHC)
Seaman WE. 1983. J. Immunol. 130:1713. (CMCD)
Cornet A, et al. 2001. Proc. Natl. Acad. Sci. USA 98:13306. (IHC)
Tsuboi S and Fukuda M. 1998. J. Biol. Chem. 273:30680. (WB) PubMed
Liu F, et al. 2012. Blood. 119:3295. PubMed
Pelletier AN, et al. 2012. J. Immunol. 188:5561. PubMed

RRID

AB_2814092 (BioLegend Cat. No. 157602)

Antigen Details

Structure

Protein tyrosine phosphatase (PTP) family, 180-240 kD

Distribution

Expressed on almost all hematopoietic cells except for mature erythrocytes.

Function

Phosphatase, T and B cell activation

Ligand/Receptor

Galectin-1, CD2, CD3, CD4, TCR, CD22, Thy-1

Cell Type

B cells, Dendritic cells, Mesenchymal Stem Cells, Tregs

Biology Area

Cell Biology, Immunology, Inhibitory Molecules, Innate Immunity, Neuroscience, Neuroscience Cell Markers, Stem Cells

Molecular Family

CD Molecules

Antigen References

Barclay AN,?et al.?1997. The Leukocyte Antigen FactsBook Academic Press.
Trowbridge IS and Thomas ML. 1994. Annu. Rev. Immunol. 12:85-116.
Kishihara K,?et al.?1993.?Cell?74:143.
Pulido R,?et al.?1988.?J. Immunol.?140:3851.

Gene ID

19264 View all products for this Gene ID

UniProt

View information about CD45 on UniProt.org

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