Ultra-LEAF™ Purified anti-human/mouse/rat CD
- 产品名称：
- Ultra-LEAF™ Purified anti-human/mouse/rat CD
- 产品类别：
- 抗体
- 产品编号：
- 395103
- 产品应用：
- 395103
- Verified Reactivity
- Human, Mouse, Rat
- Antibody Type
- Recombinant
- Host Species
- Human
- Immunogen
- Mouse T cell clone D10.G4.1
- Formulation
- 0.2 ?m filtered in phosphate-buffered solution, pH 7.2, containing no preservative. Endotoxin level is <0.01 EU/?g of the protein (<0.001 ng/?g of the protein) as determined by the LAL test.
- Preparation
- The Ultra-LEAF? (Low Endotoxin, Azide-Free) antibody was purified by affinity chromatography.
- Concentration
- The antibody is bottled at the concentration indicated on the vial, typically between 2 mg/mL and 3 mg/mL. Older lots may have also been bottled at 1 mg/mL. To obtain lot-specific concentration, please enter the lot number in our Concentration and Expiration Lookup or Certificate of Analysis online tools.
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C. This Ultra-LEAF? solution contains no preservative; handle under aseptic conditions.
- Application
-
FC - Quality tested
- Recommended Usage
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤1.0 ?g per million cells in 100 ?l volume. It is recommended that the reagent be titrated for optimal performance for each application.
- RRID
- AB_2810589 (BioLegend Cat. No. 395103) AB_2810590 (BioLegend Cat. No. 395104)
- Structure
- Type I transmembrane protein, member of the CD28/CTLA-4 family, homodimer of 47-57 kD.
- Distribution
-
Activated T cells
- Function
- Pivotal role in T cell activation, proliferation and Th1/Th2 differentiation; required for humoral immune response.
- Ligand/Receptor
- B7-H2 (ICOS-L, CD275)
- Cell Type
- T cells, Th17, Thymocytes, Tregs
- Biology Area
- Costimulatory Molecules, Immunology
- Molecular Family
- CD Molecules
- Antigen References
-
- Tahiliani V, et al. 2017. J Immunol. 198:218.
- Pedros C, et al. 2016. Nat Immunol 17:1005.
- Maazi H, et al. 2015. Immunity 42:538.
- Guedan S, et al. 2014. Blood. 124:1070.
- Weber JP, et al. 2015. J. Exp. Med. 212:217.
- Gene ID
- 29851 View all products for this Gene ID
- UniProt
- View information about CD278 on UniProt.org
