Ultra-LEAF™ Purified anti-mouse CD8a Recombi
- 产品名称：
- Ultra-LEAF™ Purified anti-mouse CD8a Recombi
- 产品类别：
- 抗体
- 产品编号：
- 155011
- 产品应用：
- 155011
- Verified Reactivity
- Mouse
- Antibody Type
- Recombinant
- Host Species
- Mouse
- Immunogen
- Mouse thymus or spleen
- Formulation
- 0.2 ?m filtered in phosphate-buffered solution, pH 7.2, containing no preservative. Endotoxin level is < 0.01 EU/?g of the protein (< 0.001 ng/?g of the protein) as determined by the LAL test.
- Preparation
- The Ultra-LEAF? (Low Endotoxin, Azide-Free) antibody was purified by affinity chromatography.
- Concentration
- The antibody is bottled at the concentration indicated on the vial, typically between 2 mg/mL and 3 mg/mL. Older lots may have also been bottled at 1 mg/mL. To obtain lot-specific concentration, please enter the lot number in our Concentration and Expiration Lookup or Certificate of Analysis online tools.
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C. This Ultra-LEAF? solution contains no preservative; handle under aseptic conditions.
- Application
-
FC - Quality tested
Depletion - Verified
- Recommended Usage
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 0.015??g per million cells in 100 ?L volume. A single i.v. dose of 200 ?g of mAb QA17A07 depletes CD8+ T cells from peripheral blood for aproximatelly 30 days. It is recommended that the reagent be titrated for optimal performance for each application.
- Product Citations
-
- Sodji QH, et al. 2022. Cancer Res Commun. 2:725. PubMed
- RRID
- AB_2888825 (BioLegend Cat. No. 155011) AB_2888825 (BioLegend Cat. No. 155012)
- Structure
- Ig superfamily, CD8α chain, 34 kD
- Distribution
-
Most thymocytes, T cell subset, some NK cells, lymphoid dendritic cells
- Function
- Co-receptor for TCR
- Ligand/Receptor
- MHC class I molecule
- Cell Type
- Dendritic cells, NK cells, T cells, Thymocytes
- Biology Area
- Immunology
- Molecular Family
- CD Molecules
- Antigen References
-
- Barclay AN, Brown MH. 1997.?Biochem. Soc. Trans.?25:224-8.
- Zamoyska R. 1994.?Immunity?1:243.
- Ellmeier W,?et al.?1999.?Annu. Rev. Immunol.?17:523.
- Gene ID
- 12525 View all products for this Gene ID
- UniProt
- View information about CD8a on UniProt.org
