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Purified anti-Keratin 5 Polyclonal Chicken Antibod
产品名称:
Purified anti-Keratin 5 Polyclonal Chicken Antibod
产品类别:
抗体
产品编号:
905903
产品应用:
905903
[价格]
规格 价格 库存
25µg ¥ 3010 1

产品详情

Product Details

Verified Reactivity
Human, Mouse
Antibody Type
Polyclonal
Host Species
Chicken
Immunogen
This monospecific polyclonal antibody was raised against a peptide sequence derived from the C-terminus of the mouse keratin 5 protein.
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation
The antibody was purified by affinity chromatography.
Concentration
0.5 mg/ml
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C.
Application

IHC-P - Quality tested

Recommended Usage

Each lot of this antibody is quality control tested by formalin-fixed paraffin-embedded immunohistochemical staining. For immunohistochemistry, a concentration range of 0.1 – 5.0 ?g/ml is suggested. It is recommended that the reagent be titrated for optimal performance for each application.

Product Citations
  1. Grbesa I, et al. 2021. Cell Rep. 36:109625. PubMed
  2. Carraro G, et al. 2020. Am J Respir Crit Care Med. 202:1540. PubMed
  3. Paris AJ, et al. 2020. Nat Cell Biol. 1.747916667. PubMed
  4. Eshiba S, et al. 2021. Cell Reports. 36(5):109492. PubMed
  5. van Ineveld RL, et al. 2022. Nat Protoc. 17:3028. PubMed
  6. Yang K, et al. 2022. J Clin Invest. 132:. PubMed
  7. Dong B, et al. 2020. Commun Biol. 3:778. PubMed
  8. Kadur Lakshminarasimha Murthy P, et al. 2022. Nature. 604:111. PubMed
  9. Keshvari S, et al. 2021. PLoS Genet. 17:e1009605. PubMed
  10. Nanba D, et al. 2021. J Cell Biol. 220:. PubMed
  11. Wei JP, et al. 2020. Exp Dermatol. 29:400. PubMed
  12. Yuan T, et al. 2020. Front Pharmacol. 11:120. PubMed
  13. Yoon YJ, et al. 2022. Nat Commun. 13:3291. PubMed
  14. Liang Z, et al. 2022. iScience. 25:105233. PubMed
RRID
AB_2721742 (BioLegend Cat. No. 905903) AB_2721743 (BioLegend Cat. No. 905904)

Antigen Details

Structure
Keratin 5 is a 590 amino acid protein with a molecular mass of 62 kD.
Distribution

Tissue distribution: esophagus, hair follicle, saliva, and skin.
Cellular distribution: cytoskeleton, extracellular, nucleus, and cytosol.

Function
Keratin 5 IFs contribute to the cell architecture and provide the cells with elasticity to withstand mechanical and non-mechanical stresses.
Interaction
Keratin 14
Biology Area
Cell Biology, Cell Motility/Cytoskeleton/Structure, Neuroscience, Neuroscience Cell Markers
Molecular Family
Intermediate Filaments
Antigen References
  1. Yuspa SH, et al 1989 J Cell Biol 109:1207.
  2. Roop, DR, et al 1984 J Biol Chem 259:8037.
Gene ID
3852 View all products for this Gene ID
UniProt
View information about Keratin 5 on UniProt.org

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