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Purified anti-AICD Antibody (Previously Covance ca
产品名称:
Purified anti-AICD Antibody (Previously Covance ca
产品类别:
抗体
产品编号:
811901
产品应用:
811901
[价格]
规格 价格 库存
50µg ¥ 7392 1

产品详情

Product Details

Verified Reactivity
Human
Antibody Type
Polyclonal
Host Species
Rabbit
Formulation
Phosphate-buffered solution.
Preparation
The antibody was purified by affinity chromatography.
Concentration
1.0 mg/mL
Storage & Handling
Do not store antibody diluted below 50 ?g/mL in the absence of protein (i.e. add 2% bovine serum albumin). The antibody solution should be stored undiluted between 2°C and 8°C. Please note the storage condition for this antibody has been changed from -20°C to between 2°C and 8°C. You can also check your vial or your CoA to find the most accurate storage condition for this antibody.
Application

ELISA
ICC?- Reported in the literature, not verified in house

Recommended Usage

Each lot of this antibody is quality control tested by ELISA assay. For ELISA applications, a concentration range of 0.01 - 1 ?g/mL is recommended. It is recommended that the reagent be titrated for optimal performance for each application.

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Application Notes

This antibody is specific for AICD (APP intracellular domain), which is a peptide fragment that results from the cleavage of C83 or C99 at the epsilon site. It does not react with the C57 or C59 γ-secretase cleavage products of APP.

This product may contain other non-IgG subtypes.

Application References

(PubMed link indicates BioLegend citation)
  1. Kaori K, et al. 2012. Invest Opththalmol Vis Sci. 53:7675-83. (WB)
  2. Stieren ES, et al. 2011. J Biol Chem. 286:35689-98. (WB)
  3. Tampellini D, et al. 2011. J Neurosci. 31:15384-90. (IF) PubMed
Product Citations
  1. Tampellini D, et al. 2011. J Neurosci. 31:15384-15390. PubMed
  2. Shang Y, et al. 2022. Acta Neuropathol. :. PubMed
  3. Hicks DA, et al. 2020. Bioscience Reports. 40(4):. PubMed
RRID
AB_2564761 (BioLegend Cat. No. 811901)

Antigen Details

Biology Area
Cell Biology, Neurodegeneration, Neuroscience, Protein Misfolding and Aggregation
Molecular Family
APP/β-Amyloid
Gene ID
351 View all products for this Gene ID
UniProt
View information about AICD on UniProt.org

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