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Purified anti-human IL-31 Antibody
产品名称:
Purified anti-human IL-31 Antibody
产品类别:
抗体
产品编号:
530002
产品应用:
530002
[价格]
规格 价格 库存
100µg ¥ 4900 1

产品详情

Product Details

Verified Reactivity
Human
Antibody Type
Polyclonal
Host Species
Goat
Immunogen
Recombinant human IL-31
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation
The antibody was purified by affinity chromatography.
Concentration
0.5 mg/ml
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C.
Application

ELISA Capture -?Quality tested

Recommended Usage

Each lot of this antibody is quality control tested by ELISA. For ELISA capture applications, a concentration of 1.0 ?g/mL is recommended. To obtain a linear standard curve, serial dilutions of IL-31 recombinant protein ranging from 2000 to 31.3 pg/mL are recommended for each ELISA plate. It is recommended that the reagent be titrated for optimal performance.

Application Notes

The purified Poly5300 antibody is useful as the capture antibody in a sandwich ELISA assay, when used in conjunction with the biotinylated Poly5300 antibody as the detecting antibody.?

RRID
AB_2650707 (BioLegend Cat. No. 530002)

Antigen Details

Structure
161 aa with a putative 23 aa signal peptide that is cleaved to generate a 138 aa mature protein.
Distribution

Secreted by activated CD4+ T cells.

Function
IL-31 belongs to the IL-6 family of cytokines and plays a role in skin inflammation.
Ligand/Receptor
Binds to IL-31 receptor complex that consists of two receptor subunits, IL31RA and OSMR.
Cell Type
T cells
Biology Area
Immunology
Molecular Family
Cytokines/Chemokines
Antigen References

1.?McCandless EE,?et al.?2014.?Vet. Immunol. Immunopathol.?157:42.
2.?Arai I,?et al.?2013.?Exp. Dermatol.?22:669.
3.?Dai X,?et al.?2013.?PLoS One.?8:e67666.
4.?Stott B,?et al.?2013.?J. Allergy Clin. Immunol.?132:446.
5.?Hartmann K,?et al.?2013.?J. Allergy Clin. Immunol.?132:232.
6.?Baron JM and Lüscher B. 2012.?Acta. Derm. Venereol.?92:5.

Gene ID
386653 View all products for this Gene ID
UniProt
View information about IL-31 on UniProt.org

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