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Purified anti-Filaggrin Antibody
产品名称:
Purified anti-Filaggrin Antibody
产品类别:
抗体
产品编号:
905804
产品应用:
905804
[价格]
规格 价格 库存
100µg ¥ 4998 1

产品详情

Product Details

Verified Reactivity
Human, Mouse
Reported Reactivity
Non-Human Primate
Antibody Type
Polyclonal
Host Species
Rabbit
Immunogen
This monospecific polyclonal antibody was raised against a peptide corresponding to residues 24-39 in the partial sequence of filaggrin.
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation
The antibody was purified by affinity chromatography.
Concentration
0.5 mg/ml
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C.
Application

IHC-F - Quality tested

Recommended Usage

Each lot of this antibody is quality control tested by immunohistochemical staining on frozen tissue sections. For immunohistochemistry, a concentration range of 1.0 - 10 μg/ml is suggested. It is recommended that the reagent be titrated for optimal performance for each application.

Application Notes


This product may contain other non-IgG subtypes.

Application References

(PubMed link indicates BioLegend citation)
  1. Wallace L, et al. 2012. J. Cell Sci. 125:1750.
  2. Bayo P, et al. 2008. Endocrinology 149:1377.
  3. Hu Y, et al. 2001. Nature 410:710.
  4. Yuspa SH, et al. 1989. J. Cell Biol. 109:1207.
  5. Liang Y. 2011. Patholog. Res. Int. 2011:936794. (IHC) PubMed
  6. Roop DR, et al. 1984. J. Biol. Chem. 259:8037.
Product Citations
  1. Miyauchi K, et al. 2021. Front Immunol. 12:663177. PubMed
  2. Baur R, et al. 2021. Toxicol Sci. 184:223. PubMed
  3. Hwang JH, et al. 2021. Int J Mol Sci. 22:00. PubMed
  4. Noguchi S, et al. 2019. Commun Biol. 2:37. PubMed
  5. Lee W, et al. 2019. Nutrients. 11. PubMed
  6. Kim SK, et al. 2022. Allergy Asthma Immunol Res. 14:549. PubMed
  7. Kim BE, et al. 2021. JCI Insight. 125:1677. PubMed
  8. Zheng H, et al. 2022. Cell Death Dis. 13:635. PubMed
RRID
AB_2616957 (BioLegend Cat. No. 905804)

Antigen Details

Structure
Filaggrin is a 44 kD protein.
Distribution

Cytoskeleton and nucleus.

Function
Mutations in this gene are associated with ichthyosis vulgaris.
Biology Area
Cell Biology, Cell Motility/Cytoskeleton/Structure
Gene ID
2312 View all products for this Gene ID
UniProt
View information about Filaggrin on UniProt.org

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