Purified anti-Keratin 5 Antibody
- 产品名称：
- Purified anti-Keratin 5 Antibody
- 产品类别：
- 抗体
- 产品编号：
- 905503
- 产品应用：
- 905503
- Verified Reactivity
- Human, Mouse, Rat
- Reported Reactivity
- Dog, Non-Human Primate
- Antibody Type
- Polyclonal
- Host Species
- Rabbit
- Immunogen
- This monospecific polyclonal antibody was raised against a peptide sequence derived from the C-terminus of the mouse keratin 5 protein.
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
- Preparation
- The antibody was purified by affinity chromatography.
- Concentration
- 0.5 mg/ml
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C.
- Application
-
IHC-P - Quality tested
WB, ICC - Verified
- Recommended Usage
Each lot of this antibody is quality control tested by formalin-fixed paraffin-embedded immunohistochemical staining. For immunohistochemisty, a concentration range of 0.2 - 5.0 μg/ml is suggested. For Western blotting, a concentration range of 0.5 - 1.0 μg/ml is suggested.?For immunocytochemistry, a concentration range of 0.5 - 1.0 μg/ml is recommended. It is recommended that the reagent be titrated for optimal performance for each application.
- Application Notes
Predicted MW is ~ 62 kD. This antibody weakly reacts with mouse.
?
This product may contain other non-IgG subtypes.
- Application References
(PubMed link indicates BioLegend citation) -
- Hübner A, et al. 2012. Proc. Natl. Acad. Sci. USA 109:12046. (IHC) PubMed
- Kierszenbaum AL, et al. 2003. Mol. Biol. Cell 14(11):4628. (IHC) PubMed
- Hu Y, et al. 2001. Nature 410:710.
- Yuspa SH, et al. 1989. J. Cell Biol. 109:1207.
- Liang Y. 2011. Patholog. Res. Int. 2011:936794. (IHC) PubMed
- Roop DR, et al. 1984. J. Biol. Chem. 259:8037.
- Product Citations
-
- Zhussupbekova S, et al. 2016. EBioMedicine. 9: 314-23. PubMed
- Taylor MS, et al. 2018. Am J Pathol. 188:1149. PubMed
- Kim M, et al. 2019. Nat Commun. 10:3991. PubMed
- Rajan A, et al. 2022. MBio. :e0351121. PubMed
- Wei Y, et al. 2022. Int J Mol Sci. 23:. PubMed
- Garcia GL, et al. 2020. Am J Pathol. 543:190. PubMed
- Abbasi S, et al. 2020. Cell Stem Cell. 27(3):396-412.e6. PubMed
- Ichijo R, et al. 2021. Sci Adv. 7:. PubMed
- Yang K, et al. 2022. J Clin Invest. 132:. PubMed
- Stewart TA, et al. 2019. Front Cell Dev Biol. 0.465277778. PubMed
- Weber MS, et al. 2021. Elife. 10: . PubMed
- Yu QC, et al. 2022. Cell Rep. 41:111694. PubMed
- Stewart TA, et al. 2020. ACS Pharmacol Transl Sci. 0.16875. PubMed
- Adams CR, et al. 2019. Elife. 8. PubMed
- Crowell PD et al. 2019. Cell Rep. 28(6):1499-1510 . PubMed
- Kim SE, et al. 2019. Anal Cell Pathol (Amst). 2018:8120579. PubMed
- Shin W, et al. 2020. Developmental Cell. 53(2):185-198. PubMed
- Nagai-Okatani C, et al. 2019. Int J Mol Sci. 20:. PubMed
- Wirasinha RC, et al. 2021. J Exp Med. 218: . PubMed
- RRID
- AB_2734679 (BioLegend Cat. No. 905503) AB_2616956 (BioLegend Cat. No. 905504)
- Structure
- Keratin 5 is a 62 kD protein.
- Distribution
-
Cytoskeleton, extracellular, and nucleus.
- Function
- Keratin 5 mutations have been associated with a complex of diseases termed epidermolysis bullosa simplex.
- Biology Area
- Cell Biology, Cell Motility/Cytoskeleton/Structure, Neuroscience, Neuroscience Cell Markers
- Molecular Family
- Intermediate Filaments
- Gene ID
- 3852 View all products for this Gene ID
- UniProt
- View information about Keratin 5 on UniProt.org
