Purified anti-Keratin 10 Antibody
- 产品名称：
- Purified anti-Keratin 10 Antibody
- 产品类别：
- 抗体
- 产品编号：
- 905403
- 产品应用：
- 905403
- Verified Reactivity
- Human, Mouse
- Reported Reactivity
- Dog, Non-Human Primate
- Antibody Type
- Polyclonal
- Host Species
- Rabbit
- Immunogen
- This monospecific polyclonal antibody was raised against a peptide sequence derived from the C-terminus of the mouse keratin 10 protein.
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
- Preparation
- The antibody was purified by affinity chromatography.
- Concentration
- 0.5 mg/ml
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C.
- Application
-
IHC-P - Quality tested
WB - Verified
- Recommended Usage
Each lot of this antibody is quality control tested by formalin-fixed paraffin-embedded immunohistochemical staining. For immunohistochemistry, a concentration range of 0.5 - 5.0 μg/ml is suggested. For Western blotting, a concentration range of 1.0 - 10 μg/ml is suggested. It is recommended that the reagent be titrated for optimal performance for each application.
- Application Notes
This product may contain other non-IgG subtypes.
- Application References
(PubMed link indicates BioLegend citation) -
- Adams JR, et al. 2011. Cancer Res. 71:2706.
- Lacroix M, et al. 2010. Proc. Natl. Acad. Sci. USA 107:21076-21081. (IHC) PubMed
- Hu Y, et al. 2001. Nature 410:710.
- Yuspa SH, et al. 1989. J. Cell Biol. 109:1207.
- Liang Y. 2011. Patholog. Res. Int. 2011:936794. (IHC) PubMed
- Roop DR, et al. 1984. J. Biol. Chem. 259:8037.
- Product Citations
-
- Byrd KM, et al. 2020. Cell Stem Cell. 25(6):814-829.e6.. PubMed
- Bordignon P et al. 2019. Cell Rep. 28(9):2358-2372 . PubMed
- Wong W, et al. 2020. PLoS One. 15:e0241617. PubMed
- Tripurani SK, et al. 2018. Mol Biol Cell. 29:2784. PubMed
- Yang K, et al. 2022. J Clin Invest. 132:. PubMed
- Villarreal-Ponce A, et al. 2020. Cell Rep. 33:108417. PubMed
- Nishiguchi MA et al. 2018. Cell reports. 24(13):3383-3392 . PubMed
- Koenig U, et al. 2019. Autophagy. :1. PubMed
- Lough KJ, et al. 2019. Elife. 8:e49249. PubMed
- Cai EY, et al. 2020. Cell Stem Cell. 27(2):270-283.e7. PubMed
- Singh DR, et al. 2022. PLoS Pathog. 18:e1010868. PubMed
- RRID
- AB_2749902 (BioLegend Cat. No. 905403) AB_2616955 (BioLegend Cat. No. 905404)
- Structure
- Keratin 10 is a 59 kD protein.
- Distribution
-
Cytoskeleton, extracellular, and nucleus.
- Function
- Keratin 10 generally associates with keratin 1. Keratin 10 mutations are associated with epidermolytic hyperkeratosis.
- Biology Area
- Cell Biology, Cell Motility/Cytoskeleton/Structure, Neuroscience, Neuroscience Cell Markers
- Molecular Family
- Intermediate Filaments
- Gene ID
- 3858 View all products for this Gene ID
- UniProt
- View information about Keratin 10 on UniProt.org
